Cellosaurus DEL (CVCL_1170)
Cell line name | DEL | ||||||||||||||||||||||||||||||||||||
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Accession | CVCL_1170 | ||||||||||||||||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: DEL (RRID:CVCL_1170) | ||||||||||||||||||||||||||||||||||||
Comments | Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines project. Part of: LL-100 blood cancer cell line panel. Part of: MD Anderson Cell Lines Project. Population: Caucasian. Virology: Contains 4 copies of an integrated murine leukemia virus closely related to that found in EKVX. Three of the integration sites are within the introns of genes OPA1, TNFRSF6B and ZNF767 (PubMed=25355872; PubMed=30629668). Doubling time: ~30 hours (DSMZ=ACC-338). Microsatellite instability: Stable (MSS) (Sanger). Omics: Genomics; DNA methylation analysis. Omics: Genomics; Whole exome sequencing. Omics: Phenotyping; Drug screening. Omics: Proteomics; Expression; Reverse-phase protein array. Omics: Proteomics; Quantitative. Omics: Transcriptomics; Microarray. Omics: Transcriptomics; RNAseq virome analysis. Omics: Transcriptomics; RNAseq. Omics: Variations; SNP array analysis. Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175. | ||||||||||||||||||||||||||||||||||||
Sequence variations |
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HLA typing | Source: PubMed=26589293
Source: DSMZCellDive=ACC-338
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Genome ancestry | Source: PubMed=30894373
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Disease | Anaplastic large cell lymphoma, ALK-positive (NCIt: C37193) ALK-positive anaplastic large cell lymphoma (ORDO: Orphanet_300895) | ||||||||||||||||||||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||||||||||||||||||||
Sex of cell | Male | ||||||||||||||||||||||||||||||||||||
Age at sampling | 12Y | ||||||||||||||||||||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||||||||||||||||||||
STR profile | Source(s): Cosmic-CLP=906836; DSMZ=ACC-338 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||||||||||||||||||
Web pages | Info; MCLP; -; https://tcpaportal.org/mclp/ | ||||||||||||||||||||||||||||||||||||
Publications | PubMed=2307542; DOI=10.1002/ijc.2910450329 PubMed=8558920 DOI=10.1016/B978-0-12-221970-2.50457-5 PubMed=15356658; DOI=10.1038/sj.leu.2403465 PubMed=17170727; DOI=10.1038/sj.leu.2404486 PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113 PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027 PubMed=25355872; DOI=10.1128/JVI.02570-14; PMCID=PMC4301145 PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469 PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076 PubMed=28356514; DOI=10.1073/pnas.1700682114; PMCID=PMC5393253 PubMed=30285677; DOI=10.1186/s12885-018-4840-5; PMCID=PMC6167786 PubMed=30629668; DOI=10.1371/journal.pone.0210404; PMCID=PMC6328144 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675 PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103 PubMed=31160637; DOI=10.1038/s41598-019-44491-x; PMCID=PMC6547646 PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775 | ||||||||||||||||||||||||||||||||||||
Cross-references | |||||||||||||||||||||||||||||||||||||
Cell line collections (Providers) | DSMZ; ACC-338 | ||||||||||||||||||||||||||||||||||||
Cell line databases/resources | CLO; CLO_0002742
cancercelllines; CVCL_1170 Cell_Model_Passport; SIDM00949 Cosmic-CLP; 906836 DepMap; ACH-000233 DSMZCellDive; ACC-338 | ||||||||||||||||||||||||||||||||||||
Biological sample resources | BioSample; SAMN03473352
BioSample; SAMN10988540 | ||||||||||||||||||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308516
ChEMBL-Targets; CHEMBL2366186 GDSC; 906836 PharmacoDB; DEL_286_2019 PubChem_Cell_line; CVCL_1170 | ||||||||||||||||||||||||||||||||||||
Encyclopedic resources | Wikidata; Q54830964 | ||||||||||||||||||||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-2770 ArrayExpress; E-MTAB-3610 ArrayExpress; E-MTAB-7721 ArrayExpress; E-MTAB-7722 GEO; GSM886976 GEO; GSM888045 GEO; GSM1669729 | ||||||||||||||||||||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 906836
Cosmic; 1086361 IARC_TP53; 21301 LiGeA; CCLE_293 Progenetix; CVCL_1170 | ||||||||||||||||||||||||||||||||||||
Proteomic databases | PRIDE; PXD030304 | ||||||||||||||||||||||||||||||||||||
Sequence databases | EGA; EGAS00001000978 | ||||||||||||||||||||||||||||||||||||
Entry history | |||||||||||||||||||||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||||||||||||||||||||
Last entry update | 10-Apr-2025 | ||||||||||||||||||||||||||||||||||||
Version number | 39 |