Cellosaurus CAS-1 (CVCL_1117)
Cell line name | CAS-1 | ||||||||||||||||||
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Synonyms | CAS1 | ||||||||||||||||||
Accession | CVCL_1117 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: CAS-1 (RRID:CVCL_1117) | ||||||||||||||||||
Comments | Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines project. Part of: TCGA-110-CL cell line panel. Population: Caucasian. Doubling time: 60 hours (PubMed=25984343). Microsatellite instability: Stable (MSS) (Sanger). Omics: Genomics; DNA methylation analysis. Omics: Genomics; Whole exome sequencing. Omics: Phenotyping; CRISPR screening. Omics: Phenotyping; Drug screening. Omics: Phenotyping; shRNA library screening. Omics: Proteomics; Quantitative. Omics: Transcriptomics; Microarray. Omics: Transcriptomics; RNAseq. Omics: Variations; SNP array analysis. Derived from site: In situ; Brain; UBERON=UBERON_0000955. | ||||||||||||||||||
Sequence variations |
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HLA typing | Source: PubMed=26589293
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Genome ancestry | Source: PubMed=30894373
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Disease | Glioblastoma (NCIt: C3058) Glioblastoma (ORDO: Orphanet_360) | ||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||
Sex of cell | Male | ||||||||||||||||||
Age at sampling | 63Y | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): Cosmic-CLP=910943 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Publications | PubMed=12635657; DOI=10.1023/A:1020630214549 PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113 PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027 PubMed=25984343; DOI=10.1038/sdata.2014.35; PMCID=PMC4432652 PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675 PubMed=30971826; DOI=10.1038/s41586-019-1103-9 PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103 PubMed=31395879; DOI=10.1038/s41467-019-11415-2; PMCID=PMC6687785 PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line collections (Providers) | ICLC; HTL97009 | ||||||||||||||||||
Cell line databases/resources | CLO; CLO_0002200
CLDB; cl4963 cancercelllines; CVCL_1117 Cell_Model_Passport; SIDM00212 Cosmic-CLP; 910943 DepMap; ACH-000464 LINCS_LDP; LCL-1369 | ||||||||||||||||||
Biological sample resources | BioSample; SAMN10987869 | ||||||||||||||||||
CRISP screens repositories | BioGRID_ORCS_Cell_line; 589 | ||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308187
ChEMBL-Targets; CHEMBL2366100 GDSC; 910943 PharmacoDB; CAS1_187_2019 PubChem_Cell_line; CVCL_1117 | ||||||||||||||||||
Encyclopedic resources | Wikidata; Q54808612 | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-2770 ArrayExpress; E-MTAB-3610 GEO; GSM886922 GEO; GSM887988 GEO; GSM1669666 | ||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 910943
Cosmic; 2367510 Cosmic; 2516014 IARC_TP53; 21216 LiGeA; CCLE_412 Progenetix; CVCL_1117 | ||||||||||||||||||
Proteomic databases | PRIDE; PXD030304 | ||||||||||||||||||
Sequence databases | EGA; EGAS00001000978 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 10-Apr-2025 | ||||||||||||||||||
Version number | 37 |