Cellosaurus logo
expasy logo

Cellosaurus AG07076 (CVCL_0N65)

[Text][XML][JSON]
Cell line name AG07076
Accession CVCL_0N65
Resource Identification Initiative To cite this cell line use: AG07076 (RRID:CVCL_0N65)
Comments Population: Caucasian.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:3439; ERCC8; Simple; p.Glu13Ter (c.37G>T); ClinVar=VCV000001716; Zygosity=Heterozygous (from autologous cell line AG07075).
  • Mutation; HGNC; HGNC:3439; ERCC8; Simple; p.Ala205Pro (c.613G>C); ClinVar=VCV000001718; Zygosity=Heterozygous (from autologous cell line AG07075).
Disease Cockayne syndrome type A (NCIt: C135725)
Cockayne syndrome (ORDO: Orphanet_191)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_0N64 ! AG07075
Sex of cell Female
Age at sampling 10Y10M
Category Finite cell line
Publications

CLPUB00597
National Institute on Aging
1994 catalog of cell lines. NIA Aging Cell Repository.
(In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda; USA (1994)

PubMed=12665480; DOI=10.1096/fj.02-0851com
Jing-Sheng Tuo, Pawel Jaruga, Henry Rodriguez, Vilhelm A. Bohr, Miral Dizdaroglu;
Primary fibroblasts of Cockayne syndrome patients are defective in cellular repair of 8-hydroxyguanine and 8-hydroxyadenine resulting from oxidative stress.
FASEB J. 17:668-674(2003)

Cross-references
Cell line collections (Providers) Coriell; AG07076
Cell line databases/resources CLO; CLO_0035648
Encyclopedic resources Wikidata; Q54740532
Entry history
Entry creation10-Apr-2015
Last entry update19-Dec-2024
Version number14