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Cellosaurus Hewga-CCS (CVCL_0J32)

[Text version]
Cell line name Hewga-CCS
Accession CVCL_0J32
Resource Identification Initiative To cite this cell line use: Hewga-CCS (RRID:CVCL_0J32)
Comments Population: Japanese.
Doubling time: ~44 hours (PubMed=24946937).
Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.
Sequence variations
  • Gene fusion; HGNC; HGNC:783; ATF1 + HGNC; HGNC:3508; EWSR1; Name(s)=EWSR1-ATF1, EWS-ATF; Note=Type 2: EWSR1 exon 7 fused to ATF1 exon 5 (PubMed=24946937; PubMed=28745431).
Disease Clear cell sarcoma of soft tissue (NCIt: C3745)
Soft tissue sarcoma (ORDO: Orphanet_3394)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 34Y
Category Cancer cell line
Publications

PubMed=24946937; DOI=10.1186/1471-2407-14-455; PMCID=PMC4076438
Hidetatsu Outani, Takaaki Tanaka, Toru Wakamatsu, Yoshinori Imura, Ken-ichiro Hamada, Nobuhito Araki, Kazuyuki Itoh, Hideki Yoshikawa, Norifumi Naka;
Establishment of a novel clear cell sarcoma cell line (Hewga-CCS), and investigation of the antitumor effects of pazopanib on Hewga-CCS.
BMC Cancer 14:455.1-455.13(2014)

PubMed=28745431; DOI=10.1002/cam4.1130; PMCID=PMC5603837
Takaaki Nakai, Yoshinori Imura, Hironari Tamiya, Shutaro Yamada, Sho Nakai, Naohiro Yasuda, Keiko Kaneko, Hidetatsu Outani, Satoshi Takenaka, Kenichiro Hamada, Akira Myoui ...Show all 16 authors... , Nobuhito Araki, Takafumi Ueda, Kazuyuki Itoh, Hideki Yoshikawa, Norifumi Naka; Show fewer authors
Trabectedin is a promising antitumor agent potentially inducing melanocytic differentiation for clear cell sarcoma.
Cancer Med. 6:2121-2130(2017)

Cross-references
Encyclopedic resources Wikidata; Q54883210
Entry history
Entry creation10-Apr-2015
Last entry update19-Dec-2024
Version number10