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Cellosaurus DTC1 (CVCL_0J31)

[Text version]
Cell line name DTC1
Synonyms DTC-1
Accession CVCL_0J31
Resource Identification Initiative To cite this cell line use: DTC1 (RRID:CVCL_0J31)
Comments Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; HGNC:783; ATF1 + HGNC; HGNC:3508; EWSR1; Name(s)=EWSR1-ATF1, EWS-ATF; Note=Type 1: EWSR1 exon 8 fused to ATF1 exon 4 (PubMed=7753552; PubMed=15150091).
Disease Clear cell sarcoma of soft tissue (NCIt: C3745)
Soft tissue sarcoma (ORDO: Orphanet_3394)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=7753552
Andrew D. Brown, Dolores H. Lopez-Terrada, Christopher T. Denny, Kevin A.W. Lee;
Promoters containing ATF-binding sites are de-regulated in cells that express the EWS/ATF1 oncogene.
Oncogene 10:1749-1756(1995)

PubMed=12966428; DOI=10.1038/sj.bjc.6601212; PMCID=PMC2376962
Kim K.C. Li, Jane Goodall, Colin Ronald Goding, Shuen-Kuei Liao, Cheng-Hsu Wang, Y.-C. Lin, Hiroaki Hiraga, Takayuki Nojima, Kazuo Nagashima, Karl-Ludwig Schaefer, Kevin A.W. Lee;
The melanocyte inducing factor MITF is stably expressed in cell lines from human clear cell sarcoma.
Br. J. Cancer 89:1072-1078(2003)

PubMed=15150091; DOI=10.1158/0008-5472.CAN-03-0809
Karl-Ludwig Schaefer, Kristin Brachwitz, Daniel H. Wai, Yvonne Braun, Raihanatou Diallo, Eberhard Korsching, Martin Eisenacher, Reinhard Voss, Frans van Valen, Claudia Baer, Barbara Selle ...Show all 18 authors... , Laura Spahn, Shuen-Kuei Liao, Kevin A.W. Lee, Pancras Cornelis Wilhelmus Hogendoorn, Guido Reifenberger, Helmut Erich Gabbert, Christopher Poremba; Show fewer authors
Expression profiling of t(12;22) positive clear cell sarcoma of soft tissue cell lines reveals characteristic up-regulation of potential new marker genes including ERBB3.
Cancer Res. 64:3395-3405(2004)

PubMed=16766266; DOI=10.1016/j.ccr.2006.04.021
Ian J. Davis, Jessica J. Kim, Fatih Ozsolak, Hans R. Widlund, Orit Rozenblatt-Rosen, Scott R. Granter, Jin-Yan Du, Jonathan A. Fletcher, Christopher T. Denny, Stephen Lee Lessnick, William Marston Linehan ...Show all 13 authors... , Andrew Li-Jen Kung, David Erich Fisher; Show fewer authors
Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT family of human cancers.
Cancer Cell 9:473-484(2006)

Cross-references
Encyclopedic resources Wikidata; Q54831557
Entry history
Entry creation10-Apr-2015
Last entry update10-Apr-2025
Version number12