Cellosaurus cell line CTC-MCC-41 (CVCL

Cellosaurus CTC-MCC-41 (CVCL_0I26)

Cross-references
Cell line name	CTC-MCC-41
Synonyms	Circulating Tumor Cells-Metastatic Colon Cancer-41
Accession	CVCL_0I26
Resource Identification Initiative	To cite this cell line use: CTC-MCC-41 (RRID:CVCL_0I26)
Comments	Doubling time: 20 hours (PubMed=25592149). Omics: Variations; CNV analysis. Donor information: Established from a colon cancer patient that presented at diagnosis a widespread disease with numerous abdominal and mediastinal metastatic lymph nodes as well as metastatic lesions in the liver (PubMed=25592149). Derived from site: Metastatic; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (PubMed=25592149; PubMed=30374140).
Disease	Colon adenocarcinoma (NCIt: C4349)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_F0X6 ! CTC-MCC-41.4 CVCL_F0X7 ! CTC-MCC-41.5A CVCL_F0X8 ! CTC-MCC-41.5B CVCL_F0X9 ! CTC-MCC-41.5C CVCL_F0XA ! CTC-MCC-41.5D CVCL_F0XB ! CTC-MCC-41.5E CVCL_F0XC ! CTC-MCC-41.5F CVCL_F0XD ! CTC-MCC-41.5G
Sex of cell	Male
Age at sampling	57Y
Category	Cancer cell line
Publications	PubMed=25592149; DOI=10.1158/0008-5472.CAN-14-2613 Laure Cayrefourcq, Thibault Mazard, Simon A. Joosse, Jerome Solassol, Jeanne Ramos, Eric Assenat, Udo Schumacher, Valerie Costes, Thierry Maudelonde, Klaus Pantel, Catherine Alix-Panabieres; Establishment and characterization of a cell line from human circulating colon cancer cells. Cancer Res. 75:892-901(2015) PubMed=30374140; DOI=10.1038/s41598-018-34365-z; PMCID=PMC6206091 Alexandra Soler, Laure Cayrefourcq, Thibault Mazard, Anna Babayan, Pierre-Jean Lamy, Said Assou, Eric Assenat, Klaus Pantel, Catherine Alix-Panabieres; Autologous cell lines from circulating colon cancer cells captured from sequential liquid biopsies as model to study therapy-driven tumor changes. Sci. Rep. 8:15931.1-15931.12(2018)
Cell line databases/resources	cancercelllines; CVCL_0I26
Encyclopedic resources	Wikidata; Q54814734
Entry history
Entry creation	10-Apr-2015
Last entry update	27-Nov-2025
Version number	13