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Cellosaurus MS1 mAKT (CVCL_0F28)

[Text version]
Cell line name MS1 mAKT
Synonyms MS1 m-Akt
Accession CVCL_0F28
Resource Identification Initiative To cite this cell line use: MS1 mAKT (RRID:CVCL_0F28)
Comments Genetic integration: Method=Transduction; Gene=MGI; MGI:87986; Akt1 (Note=With SRC myristoylation signal MGSSKSKPKDPSQR added at the N-terminus and p.Ala5_Gly130del).
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58-3).
Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
Cell type: Endothelial cell; CL=CL_0000115.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Parent: CVCL_6502 (Mile Sven 1)
Sex of cell Sex unspecified
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=17438183; DOI=10.1001/archderm.143.4.504
Perry B., Banyard J., McLaughlin E.R., Watnick R.S., Sohn A., Brindley D.N., Obata T., Cantley L.C., Cohen C., Arbiser J.L.
AKT1 overexpression in endothelial cells leads to the development of cutaneous vascular malformations in vivo.
Arch. Dermatol. 143:504-506(2007)

Cross-references
Cell line collections (Providers) ATCC; CRL-2878 - Discontinued
Encyclopedic resources Wikidata; Q54906799
Entry history
Entry creation10-Apr-2015
Last entry update10-Apr-2025
Version number13