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Cellosaurus MS1 mAKT (CVCL_0F28)

[Text version]
Cell line name MS1 mAKT
Synonyms MS1 m-Akt
Accession CVCL_0F28
Resource Identification Initiative To cite this cell line use: MS1 mAKT (RRID:CVCL_0F28)
Comments Genetic integration: Method=Transduction; Gene=MGI; MGI:87986; Akt1 (Note=With SRC myristoylation signal MGSSKSKPKDPSQR added at the N-terminus and p.Ala5_Gly130del).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58-3).
Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
Cell type: Endothelial cell; CL=CL_0000115.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Parent: CVCL_6502 (Mile Sven 1)
Sex of cell Sex unspecified
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=17438183; DOI=10.1001/archderm.143.4.504
Betsy Perry, Jacqueline Banyard, Elizabeth R. McLaughlin, Randolph Seth Watnick, Allie Sohn, David N. Brindley, Toshiyuki Obata, Lewis Clayton Cantley, Cynthia Cohen, Jack Leonard Arbiser;
AKT1 overexpression in endothelial cells leads to the development of cutaneous vascular malformations in vivo.
Arch. Dermatol. 143:504-506(2007)

Cross-references
Cell line collections (Providers) ATCC; CRL-2878 - Discontinued
Encyclopedic resources Wikidata; Q54906799
Entry history
Entry creation10-Apr-2015
Last entry update14-Aug-2025
Version number14