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Cellosaurus MO6-G3 (CVCL_0E51)

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Cell line name MO6-G3
Synonyms M06-G3; MO6G3
Accession CVCL_0E51
Resource Identification Initiative To cite this cell line use: MO6-G3 (RRID:CVCL_0E51)
Comments Characteristics: High constitutive expression of dentin phosphoprotein, type I collagen and alkaline phosphatase, characteristic of an odontoblast phenotype (PubMed=7554969).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Embryonic tooth bud, dental papilla, molar; UBERON=UBERON_0015844.
Cell type: Odontoblast; CL=CL_0000060.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: Swiss Webster (CFW).
Sex of cell Sex unspecified
Age at sampling 18FD
Category Transformed cell line
Publications

PubMed=7554969; DOI=10.3109/03008209509016988
Mary J. MacDougall, Flavia Thiemann, Hein Ta, Patti Hsu, Lian-Song Chen, Malcolm L. Snead;
Temperature sensitive simian virus 40 large T antigen immortalization of murine odontoblast cell cultures: establishment of clonal odontoblast cell line.
Connect. Tissue Res. 33:97-103(1995)

PubMed=12640734; DOI=10.1177/08959374010150010601
Mary J. MacDougall, Aaron Norman Unterbrink, David L. Carnes Jr., Sheela Rani, Xian-Hong Luan, Shuo Chen;
Utilization of MO6-G3 immortalized odontoblast cells in studies regarding dentinogenesis.
Adv. Dent. Res. 15:25-29(2001)

PubMed=16674740; DOI=10.1111/j.1365-2591.2006.01089.x
Catherine Menez-Mesgouez, Martine Oboeuf, Nicole Mauro, Pierre Colon, Mary J. MacDougall, Pierre Machtou, Jean-Michel Sautier, Ariane Berdal;
Ultrastructural and immunocytochemical characterization of immortalized odontoblast MO6-G3.
Int. Endod. J. 39:453-463(2006)

Cross-references
Encyclopedic resources Wikidata; Q54906286
Entry history
Entry creation10-Apr-2015
Last entry update14-Aug-2025
Version number14