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Cellosaurus HS-21 (CVCL_0E36)

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Cell line name HS-21
Synonyms HS21
Accession CVCL_0E36
Resource Identification Initiative To cite this cell line use: HS-21 (RRID:CVCL_0E36)
Comments Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Bone marrow, stroma; UBERON=UBERON_0007195.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=7849321; DOI=10.1182/blood.V85.4.997.bloodjournal854997
Bryan Alfred Roecklein, Beverly Torok-Storb;
Functionally distinct human marrow stromal cell lines immortalized by transduction with the human papilloma virus E6/E7 genes.
Blood 85:997-1005(1995)

Patent=US7129086
Beverly Torok-Storb, Bryan Alfred Roecklein, Gretchen Johnson;
Human marrow stromal cell lines which sustain hematopoiesis.
Patent number US7129086, 31-Oct-2006

Cross-references
Encyclopedic resources Wikidata; Q54896263
Entry history
Entry creation10-Apr-2015
Last entry update14-Aug-2025
Version number14