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Cellosaurus NZM087 (CVCL_0D47)

[Text version]
Cell line name NZM087
Synonyms NZM87
Accession CVCL_0D47
Resource Identification Initiative To cite this cell line use: NZM087 (RRID:CVCL_0D47)
Comments Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Homozygous (PubMed=32567790).
  • Mutation; HGNC; HGNC:7765; NF1; Simple; p.His1170Tyr; Zygosity=Unspecified (PubMed=32567790).
  • Mutation; HGNC; HGNC:8803; PDGFRA; Simple; p.Glu996Lys (c.2986G>A); ClinVar=VCV000822435; Zygosity=Heterozygous (PubMed=32567790).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=32567790).
HLA typing Source: PubMed=32567790
Class I
HLA-AA*02:01,03:01
HLA-BB*07:02,14:02
HLA-CC*07:02,08:02
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=32567790

Markers:
AmelogeninX,Y
CSF1PO11,13
D2S133820,24
D3S135814,15
D5S81811
D7S82010,12
D8S117911,13
D13S31711
D16S53911,13
D18S5116,17
D19S43312,13
D21S1130,32.2
FGA23,25
TH016,8
TPOX8
vWA19,20

Run an STR similarity search on this cell line
Publications

PubMed=32567790; DOI=10.1111/pcmr.12908; PMCID=PMC7818249
Khanh B. Tran, Gregory Gimenez, Peter Tsai, Sharada Kolekar, Euan J. Rodger, Aniruddha Chatterjee, Anower Jabed, Jen-Hsing Shih, Wayne R. Joseph, Elaine S. Marshall, Qian Wang ...Show all 15 authors... , Cristin Gregor Print, Michael R. Eccles, Bruce Charles Baguley, Peter R. Shepherd; Show fewer authors
Genomic and signalling pathway characterization of the NZM panel of melanoma cell lines: a valuable model for studying the impact of genetic diversity in melanoma.
Pigment Cell Melanoma Res. 34:136-143(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_0D47
Biological sample resources BioSample; SAMN14558354
Encyclopedic resources Wikidata; Q54931629
Entry history
Entry creation10-Apr-2015
Last entry update14-Aug-2025
Version number10