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Cellosaurus DD-1 [Dog hemangiosarcoma] (CVCL_0C94)

[Text version]
Cell line name DD-1 [Dog hemangiosarcoma]
Synonyms DD1
Accession CVCL_0C94
Resource Identification Initiative To cite this cell line use: DD-1 [Dog hemangiosarcoma] (RRID:CVCL_0C94)
Comments Doubling time: 5-7 days (Kerafast=EMN009-FP).
Omics: Transcriptomics; Microarray.
Caution: Was incorrectly indicated to originate from a 9 year old dog (PubMed=19461996) but is in fact from a 11 year old dog (personal communication of Modiano, Jaime F. through Kerafast).
Derived from site: In situ; Spleen; UBERON=UBERON_0002106.
Disease Canine hemangiosarcoma (NCIt: C122783)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Golden Retriever x Pyrenean mountain dog; VBO=VBO_0200610+VBO_0200629.
Sex of cell Male
Age at sampling 11Y
Category Cancer cell line
Publications

PubMed=15064773; DOI=10.1038/labinvest.3700080
Susan P. Fosmire, Erin B. Dickerson, Allyson M. Scott, Stacie R. Bianco, Marilyn J. Pettengill, Heather A. Meylemans, Marcia L. Padilla, Ashley Ann Frazer-Abel, Nasim Akhtar, David M. Getzy, John Wojcieszyn ...Show all 14 authors... , Matthew Breen, Stuart C. Helfand, Jaime F. Modiano; Show fewer authors
Canine malignant hemangiosarcoma as a model of primitive angiogenic endothelium.
Lab. Invest. 84:562-572(2004)

PubMed=16797414; DOI=10.1016/j.exphem.2006.04.013
Angela R. Lamerato-Kozicki, Karen M. Helm, Cristan M. Jubala, Gary R. Cutter, Jaime F. Modiano;
Canine hemangiosarcoma originates from hematopoietic precursors with potential for endothelial differentiation.
Exp. Hematol. 34:870-878(2006)

PubMed=19461996; DOI=10.1371/journal.pone.0005549; PMCID=PMC2680013
Beth A. Tamburini, Susan Trapp, Tzu Lip Phang, Jill T. Schappa, Lawrence E. Hunter, Jaime F. Modiano;
Gene expression profiles of sporadic canine hemangiosarcoma are uniquely associated with breed.
PLoS ONE 4:e5549.1-e5549.12(2009)

PubMed=24582862; DOI=10.1016/j.yexcr.2014.02.020; PMCID=PMC4256199
Jong-Hyuk Kim, Aric M. Frantz, Katie L. Anderson, Ashley J. Graef, Milcah C. Scott, Sally Robinson, Leslie C. Sharkey, Timothy D. O'Brien, Erin B. Dickerson, Jaime F. Modiano;
Interleukin-8 promotes canine hemangiosarcoma growth by regulating the tumor microenvironment.
Exp. Cell Res. 323:155-164(2014)

PubMed=30601866; DOI=10.1371/journal.pone.0210297; PMCID=PMC6314605
Matthew Dowling, Jonathan Samuelson, Bahaa A. Fadl-Alla, Holly C. Pondenis, Mark Byrum, Anne M. Barger, Timothy M. Fan;
Overexpression of prostate specific membrane antigen by canine hemangiosarcoma cells provides opportunity for the molecular detection of disease burdens within hemorrhagic body cavity effusions.
PLoS ONE 14:e0210297.1-e0210297.20(2019)

Cross-references
Cell line collections (Providers) Kerafast; EMN009-FP
Encyclopedic resources Wikidata; Q54828682
Gene expression databases GEO; GSM377407
GEO; GSM1122227
Entry history
Entry creation10-Apr-2015
Last entry update10-Apr-2025
Version number16