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Cellosaurus Dal-4 (CVCL_0C93)

[Text version]
Cell line name Dal-4
Synonyms DAL-4; Dal4
Accession CVCL_0C93
Resource Identification Initiative To cite this cell line use: Dal-4 (RRID:CVCL_0C93)
Comments Doubling time: 5-7 days (Kerafast=EMN018-FP).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Spleen; UBERON=UBERON_0002106.
Disease Canine hemangiosarcoma (NCIt: C122783)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Dalmatian; VBO=VBO_0200427.
Sex of cell Male
Age at sampling 7Y
Category Cancer cell line
Publications

PubMed=15064773; DOI=10.1038/labinvest.3700080
Fosmire S.P., Dickerson E.B., Scott A.M., Bianco S.R., Pettengill M.J., Meylemans H.A., Padilla M.L., Frazer-Abel A.A., Akhtar N., Getzy D.M., Wojcieszyn J., Breen M., Helfand S.C., Modiano J.F.
Canine malignant hemangiosarcoma as a model of primitive angiogenic endothelium.
Lab. Invest. 84:562-572(2004)

PubMed=16797414; DOI=10.1016/j.exphem.2006.04.013
Lamerato-Kozicki A.R., Helm K.M., Jubala C.M., Cutter G.R., Modiano J.F.
Canine hemangiosarcoma originates from hematopoietic precursors with potential for endothelial differentiation.
Exp. Hematol. 34:870-878(2006)

PubMed=19461996; DOI=10.1371/journal.pone.0005549; PMCID=PMC2680013
Tamburini B.A., Trapp S., Phang T.L., Schappa J.T., Hunter L.E., Modiano J.F.
Gene expression profiles of sporadic canine hemangiosarcoma are uniquely associated with breed.
PLoS ONE 4:e5549.1-e5549.12(2009)

PubMed=24582862; DOI=10.1016/j.yexcr.2014.02.020; PMCID=PMC4256199
Kim J.-H., Frantz A.M., Anderson K.L., Graef A.J., Scott M.C., Robinson S., Sharkey L.C., O'Brien T.D., Dickerson E.B., Modiano J.F.
Interleukin-8 promotes canine hemangiosarcoma growth by regulating the tumor microenvironment.
Exp. Cell Res. 323:155-164(2014)

PubMed=28029283; DOI=10.2460/ajvr.78.1.69; PMCID=PMC5299388
Witter L.E., Gruber E.J., Lean F.Z.-X., Stokol T.
Evaluation of procoagulant tissue factor expression in canine hemangiosarcoma cell lines.
Am. J. Vet. Res. 78:69-79(2017)

Cross-references
Cell line collections (Providers) Kerafast; EMN018-FP
Encyclopedic resources Wikidata; Q54828558
Gene expression databases GEO; GSM377405
Entry history
Entry creation10-Apr-2015
Last entry update10-Apr-2025
Version number13