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Cellosaurus UM-SCC-105 (CVCL_0C69)

[Text version]
Cell line name UM-SCC-105
Synonyms UMSCC-105; University of Michigan-Squamous Cell Carcinoma-105
Accession CVCL_0C69
Resource Identification Initiative To cite this cell line use: UM-SCC-105 (RRID:CVCL_0C69)
Comments Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Omics: Variations; CNV analysis.
Derived from site: In situ; Larynx; UBERON=UBERON_0001737.
Disease Laryngeal squamous cell carcinoma (NCIt: C4044)
Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
STR profile Source(s): PubMed=25677579

Markers:
AmelogeninX,Y
D3S135815,18
D5S81811
D7S8209,11
D8S117912,15
D13S31711,12
D18S5112,16
D21S1129,30
FGA18,21
vWA15,17

Run an STR similarity search on this cell line
Publications

PubMed=25677579; DOI=10.1002/hed.24019; PMCID=PMC4530106
John Henry Owen, Martin P. Graham, Steven B. Chinn, Owen Alan Fletcher Darr, Douglas Brian Chepeha, Gregory T. Wolf, Carol R. Bradford, Thomas E. Carey, Mark Edward P. Prince;
Novel method of cell line establishment utilizing fluorescence-activated cell sorting resulting in 6 new head and neck squamous cell carcinoma lines.
Head Neck 38 Suppl. 1:E459-E467(2016)

PubMed=28236344; DOI=10.1002/hed.24729; PMCID=PMC5392184
Heather M. Walline, Christine Marie Goudsmit, Jonathan B. McHugh, Alice L. Tang, John Henry Owen, Bin Tean Teh, Erin L. McKean, Thomas W. Glover, Martin P. Graham, Mark Edward P. Prince, Douglas Brian Chepeha ...Show all 19 authors... , Steven B. Chinn, Robert Louis Ferris, Susanne M. Gollin, Thomas K. Hoffmann, Henning Bier, Ruud H. Brakenhoff, Carol R. Bradford, Thomas E. Carey; Show fewer authors
University of Michigan Head and Neck Specialized Program of Research Excellence (SPORE) Program
Integration of high-risk human papillomavirus into cellular cancer-related genes in head and neck cancer cell lines.
Head Neck 39:840-852(2017)

PubMed=31090975; DOI=10.1002/hed.25803; PMCID=PMC6692232
Jacqueline E. Mann, Aditi Kulkarni, Andrew C. Birkeland, Judy Kafelghazal, Julia Eisenberg, Brittany M. Jewell, Megan L. Ludwig, Matthew Edward Spector, Hui Jiang, Thomas E. Carey, J. Chad Brenner;
The molecular landscape of the University of Michigan laryngeal squamous cell carcinoma cell line panel.
Head Neck 41:3114-3124(2019)

PubMed=32574978; DOI=10.1016/j.tranon.2020.100808; PMCID=PMC7317296
Thankam S. Nair, Trey B. Thomas, Lucy Yang, Bala Naveen Kakaraparthi, Anna C. Morris, Alanna M. Clark, Lora Perry Campredon, Andrew F. Brouwer, Marisa C. Eisenberg, Rafael Meza, Thomas E. Carey;
Characteristics of head and neck squamous cell carcinoma cell lines reflect human tumor biology independent of primary etiologies and HPV status.
Transl. Oncol. 13:100808.1-100808.9(2020)

Cross-references
Cell line collections (Providers) Millipore; SCC189
Cell line databases/resources cancercelllines; CVCL_0C69
Encyclopedic resources Wikidata; Q54990798
Gene expression databases GEO; GSM3631291
Polymorphism and mutation databases Progenetix; CVCL_0C69
Entry history
Entry creation10-Apr-2015
Last entry update10-Apr-2025
Version number13