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Cellosaurus NZM076 (CVCL_0B51)

[Text version]
Cell line name NZM076
Synonyms NZM76
Accession CVCL_0B51
Resource Identification Initiative To cite this cell line use: NZM076 (RRID:CVCL_0B51)
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (PubMed=32567790).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=32567790).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=32567790

Markers:
AmelogeninX
CSF1PO12
D2S133817,18
D3S135814,16
D5S81811
D7S8208,11
D8S117911,13
D13S3179,12
D16S5398,9
D18S5112,15
D19S43313,14
D21S1132.2
FGA23,24
TH017,9
TPOX8,11
vWA16,19

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Publications

PubMed=24455489; DOI=10.3389/fonc.2013.00333; PMCID=PMC3888952
Stacey Ann N. D'mello, Jack U. Flanagan, Taryn N. Green, Euphemia Yee Leung, Marjan E. Askarian-Amiri, Wayne R. Joseph, Michael R. McCrystal, Richard J. Isaacs, James H.F. Shaw, Christopher E. Furneaux, Matthew John During ...Show all 14 authors... , Graeme John Finlay, Bruce Charles Baguley, Maggie Lucy Kalev-Zylinska; Show fewer authors
Evidence that GRIN2A mutations in melanoma correlate with decreased survival.
Front. Oncol. 3:333.1-333.9(2014)

PubMed=32567790; DOI=10.1111/pcmr.12908; PMCID=PMC7818249
Khanh B. Tran, Gregory Gimenez, Peter Tsai, Sharada Kolekar, Euan J. Rodger, Aniruddha Chatterjee, Anower Jabed, Jen-Hsing Shih, Wayne R. Joseph, Elaine S. Marshall, Qian Wang ...Show all 15 authors... , Cristin Gregor Print, Michael R. Eccles, Bruce Charles Baguley, Peter R. Shepherd; Show fewer authors
Genomic and signalling pathway characterization of the NZM panel of melanoma cell lines: a valuable model for studying the impact of genetic diversity in melanoma.
Pigment Cell Melanoma Res. 34:136-143(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_0B51
Encyclopedic resources Wikidata; Q54931617
Polymorphism and mutation databases Cosmic; 2141928
Entry history
Entry creation10-Apr-2015
Last entry update14-Aug-2025
Version number9