Cellosaurus cell line 228A (CVCL

Cross-references
Cell line name	228A
Accession	CVCL_0B43
Resource Identification Initiative	To cite this cell line use: 228A (RRID:CVCL_0B43)
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly279Glu (c.836G>A); ClinVar=VCV000419454; Zygosity=Unspecified (PubMed=9620551).
Disease	Embryonal carcinoma (NCIt: C3752) Embryonal carcinoma (ORDO: Orphanet_180226)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=9620551; DOI=10.1038/sj.onc.1201770 Jane Houldsworth, Han Xiao, Vundavalli V.V.S. Murty, Wei-Yi Chen, Beevash Ray, Victor E. Reuter, George J. Bosl, Raju S.K. Chaganti; Human male germ cell tumor resistance to cisplatin is linked to TP53 gene mutation. Oncogene 16:2345-2349(1998) PubMed=24812411; DOI=10.1158/1078-0432.CCR-13-2868 Darren R. Feldman, Gopa Iyer, Lindsay Van Alstine, Sujata Patil, Hikmat Al-Ahmadie, Victor E. Reuter, George J. Bosl, Raju S.K. Chaganti, David B. Solit; Presence of somatic mutations within PIK3CA, AKT, RAS, and FGFR3 but not BRAF in cisplatin-resistant germ cell tumors. Clin. Cancer Res. 20:3712-3720(2014)
Cell line databases/resources	cancercelllines; CVCL_0B43
Encyclopedic resources	Wikidata; Q54583373
Polymorphism and mutation databases	Cosmic; 2163761
Entry history
Entry creation	10-Apr-2015
Last entry update	19-Dec-2024
Version number	10