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Cellosaurus Kasumi-3 (CVCL_0612)

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Cell line name Kasumi-3
Synonyms KASUMI-3; Kasumi 3; Kasumi3; KASUMI3
Accession CVCL_0612
Resource Identification Initiative To cite this cell line use: Kasumi-3 (RRID:CVCL_0612)
Comments Part of: MD Anderson Cell Lines Project.
Population: Japanese.
Doubling time: 55-60 hours (PubMed=8613429); ~3-4 days (DSMZ=ACC-714).
Microsatellite instability: Stable (MSS) (PubMed=10739008; PubMed=11226526).
Omics: Phenotyping; Drug screening.
Omics: Proteomics; Expression; Reverse-phase protein array.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Misspelling: Kusami-3; Cosmic=2750860.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Myeloblast; CL=CL_0000835.
Disease Adult acute myeloid leukemia with minimal differentiation (NCIt: C8303)
Acute myeloid leukemia with minimal differentiation (ORDO: Orphanet_98832)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 57Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-2725; DSMZ=ACC-714; JCRB=JCRB1004

Markers:
AmelogeninX,Y
CSF1PO11
D2S133818,26
D3S135815,16
D5S81812
D7S82010,11
D8S117914
D13S31711,12
D16S5399,11 (ATCC=CRL-2725; JCRB=JCRB1004)
11 (DSMZ=ACC-714)
D18S5114,17
D19S43314,15
D21S1130
FGA20,24
Penta D9,11
Penta E16
TH016,9 (DSMZ=ACC-714; JCRB=JCRB1004)
6,9,11 (ATCC=CRL-2725)
TPOX8
vWA16,18

Run an STR similarity search on this cell line
Web pages Info; -; -; https://web.archive.org/web/20201109215324/www.infarktforschung.de/macrophages_cell_lines.html
Info; MCLP; -; https://tcpaportal.org/mclp/
Publications

PubMed=8613429; DOI=10.1111/j.1349-7006.1996.tb00216.x; PMCID=PMC5921094
Hiroya Asou, Kazumi Suzukawa, Kenkichi Kita, Kazunori Nakase, Haruo Ueda, Kazuhiro Morishita, Nanao Kamada;
Establishment of an undifferentiated leukemia cell line (Kasumi-3) with t(3;7)(q27;q22) and activation of the EVI1 gene.
Jpn. J. Cancer Res. 87:269-274(1996)

PubMed=10739008; DOI=10.1016/S0145-2126(99)00182-4
Kaoru Inoue, Takashi Kohno, Satoshi Takakura, Yasuhide Hayashi, Hideaki Mizoguchi, Jun Yokota;
Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines.
Leuk. Res. 24:255-262(2000)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=11226526; DOI=10.1016/S0145-2126(00)00121-1
Kaoru Inoue, Takashi Kohno, Satoshi Takakura, Yasuhide Hayashi, Hideaki Mizoguchi, Jun Yokota;
Corrigendum to: Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines Leukemia Research 24 (2000), 255-262.
Leuk. Res. 25:275-278(2001)

PubMed=14504097; DOI=10.1182/blood-2003-02-0418
Takeshi Taketani, Tomohiko Taki, Kanji Sugita, Yoshiyuki Furuichi, Eiichi Ishii, Ryoji Hanada, Masahiro Tsuchida, Kenichi Sugita, Kohmei Ida, Yasuhide Hayashi;
FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy.
Blood 103:1085-1088(2004)

PubMed=23955599; DOI=10.1038/ng.2731
Ayana Kon, Lee-Yung Shih, Masashi Minamino, Masashi Sanada, Yuichi Shiraishi, Yasunobu Nagata, Ken-ichi Yoshida, Yusuke Okuno, Masashige Bando, Ryuichiro Nakato, Shumpei Ishikawa ...Show all 41 authors... , Aiko Sato-Otsubo, Genta Nagae, Aiko Nishimoto, Claudia Haferlach, Daniel Nowak, Yusuke Sato, Tamara Alpermann, Masao Nagasaki, Teppei Shimamura, Hiroko Tanaka, Kenichi Chiba, Ryo Yamamoto, Tomoyuki Yamaguchi, Makoto Otsu, Naoshi Obara, Mamiko Sakata-Yanagimoto, Tsuyoshi Nakamaki, Ken Ishiyama, Florian Nolte, Wolf-Karsten Hofmann, Shuichi Miyawaki, Shigeru Chiba, Hiraku Mori, Hiromitsu Nakauchi, Harold Phillip Koeffler, Hiroyuki Aburatani, Torsten Haferlach, Katsuhiko Shirahige, Satoru Miyano, Seishi Ogawa; Show fewer authors
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.
Nat. Genet. 45:1232-1237(2013)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
Jun Li, Wei Zhao, Rehan Akbani, Wen-Bin Liu, Zhen-Lin Ju, Shi-Yun Ling, Christopher P. Vellano, Paul Roebuck, Qing-Hua Yu, A. Karina Eterovic, Lauren Averett Byers ...Show all 25 authors... , Michael A. Davies, Wan-Leng Deng, Y.N. Vashisht Gopal, Guo Chen, Erika Maria von Euw, Dennis Joseph Slamon, Dylan Conklin, John Victor Heymach, Adi F. Gazdar, John D. Minna, Jeffrey N. Myers, Yi-Ling Lu, Gordon B. Mills, Han Liang; Show fewer authors
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=32180206; DOI=10.1007/s13577-020-00347-5; PMCID=PMC7324421
Fumio Kasai, Hiroya Asou, Midori Ozawa, Kazuhiko Kobayashi, Hiroyuki Kuramitsu, Motonobu Satoh, Arihiro Kohara, Yasuhiko Kaneko, Machiko Kawamura;
Kasumi leukemia cell lines: characterization of tumor genomes with ethnic origin and scales of genomic alterations.
Hum. Cell 33:868-876(2020)

PubMed=36982453; DOI=10.3390/ijms24065377; PMCID=PMC10049680
Rafal Skopek, Malgorzata Palusinska, Katarzyna Kaczor-Keller, Rafal Pingwara, Anna Papierniak-Wygladala, Tino Schenk, Slawomir Lewicki, Artur Zelent, Lukasz Szymanski;
Choosing the right cell line for acute myeloid leukemia (AML) research.
Int. J. Mol. Sci. 24:5377.1-5377.34(2023)

Cross-references
Cell line collections (Providers) ATCC; CRL-2725
DSMZ; ACC-714
JCRB; JCRB1004
JCRB; NIHS0236 - Discontinued
Cell line databases/resources CLO; CLO_0007070
DSMZCellDive; ACC-714
Biological sample resources BioSample; SAMN01821573
BioSample; SAMN01821689
BioSample; SAMN03471777
BioSample; SAMN03472527
BioSample; SAMN03473397
Chemistry resources GDSC; 1327776
PharmacoDB; Kasumi3_735_2019
Encyclopedic resources Wikidata; Q54899520
Gene expression databases FANTOM5_SSTAR; 10789-110H6
GEO; GSM1374591
GEO; GSM4254131
Polymorphism and mutation databases Cosmic; 787442
Cosmic; 975259
Cosmic; 996310
Cosmic; 1037659
Cosmic; 2089647
Cosmic; 2750860
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number30