Cellosaurus cell line WiT49 (CVCL

Cellosaurus WiT49 (CVCL_0583)

Cross-references
Cell line name	WiT49
Synonyms	WiT 49
Accession	CVCL_0583
Resource Identification Initiative	To cite this cell line use: WiT49 (RRID:CVCL_0583)
Comments	Characteristics: Established from a first-generation nude mouse subcutaneous xenograft. Derived from site: Metastatic; Lung; UBERON=UBERON_0002048.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Unspecified (PubMed=14506735).
Disease	Kidney Wilms tumor (NCIt: C40407) Nephroblastoma (ORDO: Orphanet_654)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	24Y
Category	Cancer cell line
Web pages	Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/w/cell-lines-detail-622.html
Publications	PubMed=8623926; PMCID=PMC1861544 Chitra Lahoti, Paul Scott Thorner, David Malkin, Herman Yeger; Immunohistochemical detection of p53 in Wilms' tumors correlates with unfavorable outcome. Am. J. Pathol. 148:1577-1589(1996) PubMed=14506735; DOI=10.1002/ijc.11429 Jennifer Alami, Bryan Raymond George Williams, Herman Yeger; Derivation and characterization of a Wilms' tumour cell line, WiT 49. Int. J. Cancer 107:365-374(2003) PubMed=19824073; DOI=10.1002/pbc.22205; PMCID=PMC2834252 Mei-Hong Li, Harold Yamase, Fernando Ferrer; Characterization of a WiT49 cell line derived orthotopic model of Wilms tumor. Pediatr. Blood Cancer 54:316-318(2010)
Cell line databases/resources	MCCL; MCC:0000489 cancercelllines; CVCL_0583
Encyclopedic resources	Wikidata; Q54994118
Polymorphism and mutation databases	Cosmic; 1196557 IARC_TP53; 18935
Entry history
Entry creation	04-Apr-2012
Last entry update	10-Apr-2025
Version number	18