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Cellosaurus WAC2 (CVCL_0575)

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Cell line name WAC2
Synonyms WAC-2; WAC 2
Accession CVCL_0575
Resource Identification Initiative To cite this cell line use: WAC2 (RRID:CVCL_0575)
Comments Population: Caucasian.
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Mutation; HGNC; HGNC:427; ALK; Simple; p.Phe1174Leu (c.3522C>A); ClinVar=VCV000217852; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0522 (SH-EP007)
Sex of cell Female
Age at sampling 4Y
Category Cancer cell line
Publications

PubMed=2364393
Lothar Schweigerer, Stephen Breit, Achim Wenzel, Kentaro Tsunamoto, Rolf Ludwig, Manfred Schwab;
Augmented MYCN expression advances the malignant phenotype of human neuroblastoma cells: evidence for induction of autocrine growth factor activity.
Cancer Res. 50:4411-4416(1990)

Cross-references
Cell line databases/resources MCCL; MCC:0000481
cancercelllines; CVCL_0575
Encyclopedic resources Wikidata; Q54993536
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number17