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Cellosaurus UM-SCV-6 (CVCL_0569)

[Text version]
Cell line name UM-SCV-6
Synonyms UMSCV-6; University of Michigan-Squamous cell Carcinoma of the Vulva-6
Accession CVCL_0569
Resource Identification Initiative To cite this cell line use: UM-SCV-6 (RRID:CVCL_0569)
Comments Virology: Contains an integrated HPV16 genome.
Doubling time: 53 hours (PubMed=15047230).
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Vulva; UBERON=UBERON_0000997.
Sequence variations
Disease Vulvar squamous cell carcinoma (NCIt: C4052)
Vulvar squamous cell carcinoma (ORDO: Orphanet_494448)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 43Y
Category Cancer cell line
Publications

PubMed=1777413; DOI=10.1002/gcc.2870030604
Worsham M.J., Van Dyke D.L., Grenman S.E., Grenman R., Hopkins M.P., Roberts J.A., Gasser K.M., Schwartz D.R., Carey T.E.
Consistent chromosome abnormalities in squamous cell carcinoma of the vulva.
Genes Chromosomes Cancer 3:420-432(1991)

PubMed=7503188; DOI=10.1016/0002-9378(95)90636-3
Hietanen S.H., Kurvinen K., Syrjanen K.J., Grenman S.E., Carey T.E., McClatchey K.D., Syrjanen S.M.
Mutation of tumor suppressor gene p53 is frequently found in vulvar carcinoma cells.
Am. J. Obstet. Gynecol. 173:1477-1482(1995)

PubMed=7599042; DOI=10.1038/bjc.1995.289; PMCID=PMC2034151
Hietanen S.H., Grenman S.E., Syrjanen K.J., Lappalainen K., Kauppinen J., Carey T.E., Syrjanen S.M.
Human papillomavirus in vulvar and vaginal carcinoma cell lines.
Br. J. Cancer 72:134-139(1995)

PubMed=9887230; DOI=10.1006/gyno.1998.5194
Rantanen V., Grenman S.E., Kurvinen K., Hietanen S.H., Raitanen M., Syrjanen S.M.
p53 mutations and presence of HPV DNA do not correlate with radiosensitivity of gynecological cancer cell lines.
Gynecol. Oncol. 71:352-358(1998)

CLPUB00591
Seppanen M.
Cytokines and gynecological cancer. In vitro effects of cytokines on ovarian, endometrial and vulvar carcinoma cells.
Thesis PhD (2000); Tampere University; Tampere; Finland

PubMed=15047230; DOI=10.1016/j.ygyno.2003.12.033
Raitanen M., Worsham M.J., Lakkala T., Carey T.E., Van Dyke D.L., Grenman R., Klemi P., Rantanen V., Isola J.J., Grenman S.E.
Characterization of 10 vulvar carcinoma cell lines by karyotyping, comparative genomic hybridization and flow cytometry.
Gynecol. Oncol. 93:155-163(2004)

Cross-references
Cell line databases/resources MCCL; MCC:0000474
Encyclopedic resources Wikidata; Q54990966
Polymorphism and mutation databases IARC_TP53; 21682
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number21