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Cellosaurus UM-SCV-6 (CVCL_0569)

[Text version]
Cell line name UM-SCV-6
Synonyms UMSCV-6; University of Michigan-Squamous cell Carcinoma of the Vulva-6
Accession CVCL_0569
Resource Identification Initiative To cite this cell line use: UM-SCV-6 (RRID:CVCL_0569)
Comments Virology: Contains an integrated HPV16 genome.
Doubling time: 53 hours (PubMed=15047230).
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Vulva; UBERON=UBERON_0000997.
Sequence variations
Disease Vulvar squamous cell carcinoma (NCIt: C4052)
Vulvar squamous cell carcinoma (ORDO: Orphanet_494448)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 43Y
Category Cancer cell line
Publications

PubMed=1777413; DOI=10.1002/gcc.2870030604
Maria J. Worsham, Daniel L. Van Dyke, Seija E. Grenman, Reidar Grenman, Michael P. Hopkins, James A. Roberts, Kathleen M. Gasser, Donald R. Schwartz, Thomas E. Carey;
Consistent chromosome abnormalities in squamous cell carcinoma of the vulva.
Genes Chromosomes Cancer 3:420-432(1991)

PubMed=7503188; DOI=10.1016/0002-9378(95)90636-3
Sakari H. Hietanen, Kaisa Kurvinen, Kari Juhani Syrjanen, Seija E. Grenman, Thomas E. Carey, Kenneth Donald McClatchey, Stina M. Syrjanen;
Mutation of tumor suppressor gene p53 is frequently found in vulvar carcinoma cells.
Am. J. Obstet. Gynecol. 173:1477-1482(1995)

PubMed=7599042; DOI=10.1038/bjc.1995.289; PMCID=PMC2034151
Sakari H. Hietanen, Seija E. Grenman, Kari Juhani Syrjanen, Katriina Lappalainen, Juha Kauppinen, Thomas E. Carey, Stina M. Syrjanen;
Human papillomavirus in vulvar and vaginal carcinoma cell lines.
Br. J. Cancer 72:134-139(1995)

PubMed=9887230; DOI=10.1006/gyno.1998.5194
Virpi Rantanen, Seija E. Grenman, Kaisa Kurvinen, Sakari H. Hietanen, Misa Raitanen, Stina M. Syrjanen;
p53 mutations and presence of HPV DNA do not correlate with radiosensitivity of gynecological cancer cell lines.
Gynecol. Oncol. 71:352-358(1998)

CLPUB00591
Marjo Seppanen;
Cytokines and gynecological cancer. In vitro effects of cytokines on ovarian, endometrial and vulvar carcinoma cells.
Thesis PhD (2000); Tampere University; Tampere; Finland

PubMed=15047230; DOI=10.1016/j.ygyno.2003.12.033
Misa Raitanen, Maria J. Worsham, Taina Lakkala, Thomas E. Carey, Daniel L. Van Dyke, Reidar Grenman, Pekka Klemi, Virpi Rantanen, Jorma J. Isola, Seija E. Grenman;
Characterization of 10 vulvar carcinoma cell lines by karyotyping, comparative genomic hybridization and flow cytometry.
Gynecol. Oncol. 93:155-163(2004)

Cross-references
Cell line databases/resources MCCL; MCC:0000474
Encyclopedic resources Wikidata; Q54990966
Polymorphism and mutation databases IARC_TP53; 21682
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number21