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Cellosaurus SW13 (CVCL_0542)

[Text version]
Cell line name SW13
Synonyms SW-13; SW 13; Scott and White No. 13
Accession CVCL_0542
Resource Identification Initiative To cite this cell line use: SW13 (RRID:CVCL_0542)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
From: Scott and White Clinic; Temple; USA.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: Deep quantitative proteome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Derived from sampling site: Adrenal gland.
Sequence variations
  • Mutation; HGNC; 11100; SMARCA4; Simple; p.Gln164Ter (c.490C>T); ClinVar=VCV001436624; Zygosity=Heterozygous (Cosmic-CLP; DepMap).
  • Mutation; HGNC; 11998; TP53; Simple; p.His193Tyr (c.577C>T); ClinVar=VCV000230256; Zygosity=Homozygous (ATCC; Cosmic-CLP; DepMap).
Genome ancestry Source: PubMed=30894373

Origin% genome
Native American0
East Asian, North0
East Asian, South0.61
South Asian0.44
European, North72.28
European, South24.66
Disease Adrenal cortex carcinoma (NCIt: C9325)
Adrenocortical carcinoma (ORDO: Orphanet_1501)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_WY51 (SW13/cl.1 vim+)CVCL_WY52 (SW13/cl.2 vim-)
Sex of cell Female
Age at sampling 55Y
Category Cancer cell line
STR profile Source(s): ATCC; CCRID; CLS; Cosmic-CLP; DepMap; ECACC; JCRB; KCLB

CSF1PO11,12 (ATCC; Cosmic-CLP; DepMap; KCLB)
D5S81811,12 (CCRID; CLS; DepMap; JCRB; KCLB)
12 (ATCC; Cosmic-CLP; ECACC)
Penta D10,13
Penta E7,15
TH017 (JCRB)
7,8 (ATCC; CCRID; CLS; Cosmic-CLP; DepMap; ECACC; KCLB)

Run an STR similarity search on this cell line
Web pages http://www.cells-talk.com/index.php/page/copelibrary?key=SW-13

Leibovitz A., McCombs W.B. III, Johnston D., McCoy C.E., Stinson J.C.
Two new human cancer cell lines.
In Vitro 8:433-434(1973)

Leibovitz A.
Development of media for isolation and cultivation of human cancer cells.
(In) Human tumor cells in vitro; Fogh J. (eds.); pp.23-50; Springer; New York (1975)

PubMed=327080; DOI=10.1093/jnci/59.1.221
Fogh J., Fogh J.M., Orfeo T.
One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice.
J. Natl. Cancer Inst. 59:221-226(1977)

PubMed=833871; DOI=10.1093/jnci/58.2.209
Fogh J., Wright W.C., Loveless J.D.
Absence of HeLa cell contamination in 169 cell lines derived from human tumors.
J. Natl. Cancer Inst. 58:209-214(1977)

PubMed=924690; DOI=10.1002/ijc.2910200505
Kerbel R.S., Pross H.F., Leibovitz A.
Analysis of established human carcinoma cell lines for lymphoreticular-associated membrane receptors.
Int. J. Cancer 20:673-679(1977)

Williams R.D.
Human urologic cancer cell lines.
Invest. Urol. 17:359-363(1980)

Rousset M., Zweibaum A., Fogh J.
Presence of glycogen and growth-related variations in 58 cultured human tumor cell lines of various tissue origins.
Cancer Res. 41:1165-1170(1981)

PubMed=3518877; DOI=10.3109/07357908609038260
Fogh J.
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

Yoshimoto K., Iwahana H., Fukuda A., Sano T., Saito S., Itakura M.
Role of p53 mutations in endocrine tumorigenesis: mutation detection by polymerase chain reaction-single strand conformation polymorphism.
Cancer Res. 52:5061-5064(1992)

PubMed=11414198; DOI=10.1007/s004320000207
Lahm H., Andre S., Hoeflich A., Fischer J.R., Sordat B., Kaltner H., Wolf E., Gabius H.J.
Comprehensive galectin fingerprinting in a panel of 61 human tumor cell lines by RT-PCR and its implications for diagnostic and therapeutic procedures.
J. Cancer Res. Clin. Oncol. 127:375-386(2001)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=21924324; DOI=10.1016/j.mce.2011.08.041
Wang T., Rainey W.E.
Human adrenocortical carcinoma cell lines.
Mol. Cell. Endocrinol. 351:58-65(2012)

PubMed=22266826; DOI=10.1055/s-0031-1298019
Wang T., Rowland J.G., Parmar J., Nesterova M., Seki T., Rainey W.E.
Comparison of aldosterone production among human adrenocortical cell lines.
Horm. Metab. Res. 44:245-250(2012)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010
Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N., Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J., Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L., Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S., Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B., Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)

Cell line collections ATCC; CCL-105
BCRC; 60483
BCRJ; 0300
CLS; 300349
ECACC; 87031801
KCB; KCB 200780YJ
KCLB; 10105
Cell line databases/resources CLO; CLO_0009185
CLO; CLO_0009209
MCCL; MCC:0000444
CLDB; cl4435
CLDB; cl4436
CCRID; 1101HUM-PUMC000055
Cell_Model_Passport; SIDM00814
Cosmic-CLP; 909744
DepMap; ACH-001401
TOKU-E; 3228
Biological sample resources BioSample; SAMN03472418
BioSample; SAMN03472692
Chemistry resources ChEMBL-Cells; CHEMBL3308467
ChEMBL-Targets; CHEMBL1075587
GDSC; 909744
PharmacoDB; SW13_1529_2019
PubChem_Cell_line; CVCL_0542
Encyclopedic resources Wikidata; Q54971076
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
GEO; GSM827353
GEO; GSM1670498
Polymorphism and mutation databases Cosmic; 684683
Cosmic; 909744
Cosmic; 1024274
Cosmic; 1179077
Cosmic; 1622872
Cosmic; 2239456
IARC_TP53; 2946
Progenetix; CVCL_0542
Proteomic databases PRIDE; PXD030304
Sequence databases EGA; EGAS00001000978
Entry history
Entry creation04-Apr-2012
Last entry update21-Mar-2023
Version number40