Cellosaurus logo
expasy logo

Cellosaurus SV80 (CVCL_0541)

[Text version]
Cell line name SV80
Synonyms SV-80; SV 80; SV-A clone 80; SV clone 80; Simian virus 80
Accession CVCL_0541
Resource Identification Initiative To cite this cell line use: SV80 (RRID:CVCL_0541)
Comments Problematic cell line: Probably misidentified. Said to originate from fibroblasts of the lung of a male black individual (CLS=300345), but in reality seems to be established from skin fibroblast of an adult female (strain A). Note that some papers have probably missasigned it to be from a Fanconi anemia patient.
Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
STR profile Source(s): CLS=300345

Markers:
AmelogeninX
CSF1PO12
D3S135816
D5S81812
D7S82010
D8S117911,15
D13S31712
D16S5399,13
D18S5115,20
D21S1128,30
FGA21,27
Penta D9
Penta E11,12
TH019
TPOX10,11
vWA16

Run an STR similarity search on this cell line
Publications

PubMed=14086148; DOI=10.1002/jcp.1030620305
George J. Todaro, Sandra R. Wolman, Howard Green;
Rapid transformation of human fibroblasts with low growth potential into established cell lines by SV40.
J. Cell. Comp. Physiol. 62:257-265(1963)

PubMed=4288245; DOI=10.1126/science.153.3741.1252
George J. Todaro, Howard Green, Michael R. Swift;
Susceptibility of human diploid fibroblast strains to transformation by SV40 virus.
Science 153:1252-1254(1966)

PubMed=4359949; DOI=10.1128/JVI.12.4.711-720.1973; PMCID=PMC356689
Raoul E. Benveniste, George J. Todaro, Edward M. Scolnick, Wade P. Parks;
Partial transcription of murine type C viral genomes in BALB c cell lines.
J. Virol. 12:711-720(1973)

PubMed=4129832; DOI=10.1093/jnci/52.1.167
George J. Todaro, Charlotte A. Meyer;
Transformation assay for murine sarcoma viruses using a simian virus 40-transformed human cell line.
J. Natl. Cancer Inst. 52:167-171(1974)

PubMed=4370249; DOI=10.1016/0092-8674(74)90041-5
Isaac Craig Henderson, David Morse Livingston;
Partial purification and characterization of the SV40 T antigen.
Cell 3:65-70(1974)

PubMed=174085; DOI=10.1073/pnas.72.12.4971; PMCID=PMC388856
Charles Dean Stiles, Walter Desmond Jr., Gordon Hisashi Sato, Milton H. Saier Jr.;
Failure of human cells transformed by simian virus 40 to form tumors in athymic nude mice.
Proc. Natl. Acad. Sci. U.S.A. 72:4971-4975(1975)

PubMed=1260760
Charles Dean Stiles, Walter Desmond Jr., Lorraine M. Chuman, Gordon Hisashi Sato, Milton H. Saier Jr.;
Growth control of heterologous tissue culture cells in the congenitally athymic nude mouse.
Cancer Res. 36:1353-1360(1976)

PubMed=68015; DOI=10.1002/ijc.2910190509
Rolf M. Flugel, T. Crefeld, Klaus Munk;
Detection of SV40 T antigen with labelled antibodies: radioimmunoassay and autoradiography.
Int. J. Cancer 19:656-663(1977)

PubMed=6328024; DOI=10.1128/JVI.50.3.943-946.1984; PMCID=PMC255757
Claudia Gruss, Ernst Baumann, Rolf Knippers;
DNA binding properties of a mutant T antigen from the simian virus 40-transformed human cell line simian virus 80.
J. Virol. 50:943-946(1984)

Cross-references
Cell line collections (Providers) ATCC; CRL-7725 - Discontinued
CLS; 300345
Cell line databases/resources MCCL; MCC:0000442
Encyclopedic resources Wikidata; Q54970989
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number16