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Cellosaurus ST15A (CVCL_0537)

[Text version]
Cell line name ST15A
Synonyms St15A
Accession CVCL_0537
Resource Identification Initiative To cite this cell line use: ST15A (RRID:CVCL_0537)
Comments Characteristics: At the permissive temperature (33 Celsius) proliferates. At the restrictive temperature (39 Celsius) has reduced proliferation and the cells can differentiate into either neurons or glial cells depending on the culture conditions.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Brain, cerebellum; UBERON=UBERON_0002037.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Sprague Dawley; RS=RS_0000681.
Sex of cell Sex unspecified
Age at sampling 2D
Category Conditionally immortalized cell line
Publications

PubMed=2856096; DOI=10.1016/0896-6273(88)90175-4
Kristen Frederiksen, Parmjit S. Jat, Nicole L.M. Valtz, Dan J. Levy, Ronald Davies Graham McKay;
Immortalization of precursor cells from the mammalian CNS.
Neuron 1:439-448(1988)

PubMed=2065021
Nicole L.M. Valtz, Timothy E. Hayes, Thor Norregaard, Shu-Mo Liu, Ronald Davies Graham McKay;
An embryonic origin for medulloblastoma.
New Biol. 3:364-371(1991)

Patent=US5270191
Ronald Davies Graham McKay, Parmjit S. Jat, Guillermina Almazan;
Method for manipulation of the cell types of eukaryotes.
Patent number US5270191, 14-Dec-1993

Cross-references
Cell line databases/resources MCCL; MCC:0000438
Encyclopedic resources Wikidata; Q54955749
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number16