Cellosaurus cell line SGHPL-4 (CVCL_0521)

Cellosaurus SGHPL-4 (CVCL_0521)

Cell line name

SGHPL-4

Synonyms

SGHPL4; CTB-CL-MC4; MC4; Saint Georges Hospital Placental cell Line-4

Accession

CVCL_0521

Resource Identification Initiative

To cite this cell line use: SGHPL-4 (RRID:CVCL_0521)

Comments

Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV3-neo).
Misspelling: SHGPL-4; Note=Once in text of PubMed=24103555.
Derived from site: In situ; Trophoblast, extravillous; UBERON=UBERON_0000426.

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Children:

CVCL_WN35 (SGHPL-4sG1)

Sex of cell

Male

Age at sampling

<12FW

Category

Transformed cell line

Publications

PubMed=9804259; DOI=10.1093/humrep/13.10.2941
Mei-Yee Choy, Isaac T. Manyonda;
The phagocytic activity of human first trimester extravillous trophoblast.
Hum. Reprod. 13:2941-2949(1998)

PubMed=10498850; DOI=10.1038/sj.bjp.0702757; PMCID=PMC1571601
Judith Eleanor Cartwright, Desmond P. Holden, Guy St J. Whitley;
Hepatocyte growth factor regulates human trophoblast motility and invasion: a role for nitric oxide.
Br. J. Pharmacol. 128:181-189(1999)

PubMed=11723542
Mei-Yee Choy, Guy St J. Whitley, Isaac T. Manyonda;
Efficient, rapid and reliable establishment of human trophoblast cell lines using poly-L-ornithine.
Early Pregnancy 4:124-143(2000)

PubMed=19223288; DOI=10.1093/humrep/dep026
James McCormick, Guy St J. Whitley, Philippe Le Bouteiller, Judith Eleanor Cartwright;
Soluble HLA-G regulates motility and invasion of the trophoblast-derived cell line SGHPL-4.
Hum. Reprod. 24:1339-1345(2009)

Cross-references

Cell line databases/resources

MCCL; MCC:0000419
Lonza; 1281

Anatomy/cell type resources

BTO; BTO_0003980

Encyclopedic resources

Wikidata; Q54953186

Entry history

Entry creation

04-Apr-2012

Last entry update

14-Aug-2025

Version number

17