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Cellosaurus PLJ-4.7 (CVCL_0486)

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Cell line name PLJ-4.7
Synonyms PLJ-47; CFPAC-PLJ-4.7; PLJ-CFTR-4.7
Accession CVCL_0486
Resource Identification Initiative To cite this cell line use: PLJ-4.7 (RRID:CVCL_0486)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:1884; CFTR.
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Gene deletion; HGNC; HGNC:6770; SMAD4; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys242Arg (c.724T>C); ClinVar=VCV000449512; Zygosity=Homozygous (from parent cell line).
Disease Cystic fibrosis (NCIt: C2975)
Pancreatic ductal adenocarcinoma (NCIt: C9120)
Cystic fibrosis (ORDO: Orphanet_586)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1119 (CFPAC-1)
Sex of cell Male
Age at sampling 26Y
Category Cancer cell line
Cross-references
Cell line databases/resources MCCL; MCC:0000385
cancercelllines; CVCL_0486
Encyclopedic resources Wikidata; Q54947580
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number22