Cellosaurus cell line NRK-52E (CVCL

Cellosaurus NRK-52E (CVCL_0468)

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Cell line name

NRK-52E

Synonyms

NRK 52E; NRK52E; NRK clone 52E; Normal Rat Kidney-52E; NRK-E52

Accession

CVCL_0468

Resource Identification Initiative

To cite this cell line use: NRK-52E (RRID:CVCL_0468)

Comments

Doubling time: ~45 hours (DSMZ=ACC-199).
Omics: Proteomics; Quantitative.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.

Species of origin

Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Osborne-Mendel; RS=RS_0000629.

Hierarchy

Parent: CVCL_3758 (NRK)
Children:

CVCL_F1SN (HyCyte NRK-52E KO-rMapk8)

CVCL_F1SP (HyCyte NRK-52E KO-rMapk9)

CVCL_E1AA (Ubigene NRK-52E Slc39a7 KO)

Category

Spontaneously immortalized cell line

Web pages

Info; ATCC; -; https://www.atcc.org/en/support/technical-support/faqs/lifespan-of-the-cell-line-nrk-52e-atcc-crl-1571

Publications

PubMed=304450; DOI=10.1002/jcp.1040940311
Joseph E. De Larco, George J. Todaro;
Epithelioid and fibroblastic rat kidney cell clones: epidermal growth factor (EGF) receptors and the effect of mouse sarcoma virus transformation.
J. Cell. Physiol. 94:335-342(1978)

PubMed=7732277; DOI=10.1177/019262339402200604
Myrtle A. Davis, Mary W. Smith, Seung H. Chang, Benjamin Franklin Trump;
Characterization of a renal epithelial cell model of apoptosis using okadaic acid and the NRK-52E cell line.
Toxicol. Pathol. 22:595-605(1994)

PubMed=29460274; DOI=10.1002/bit.26574
Jose Yeste, Laura Martinez-Gimeno, Xavi Illa, Pablo Laborda, Anton Guimera, Juan P. Sanchez-Marin, Rosa Villa, Ignacio Gimenez;
A perfusion chamber for monitoring transepithelial NaCl transport in an in vitro model of the renal tubule.
Biotechnol. Bioeng. 115:1604-1613(2018)

PubMed=33122286; DOI=10.1681/ASN.2020010009; PMCID=PMC7894662
Syed J. Khundmiri, Li-He Chen, Eleanor D. Lederer, Chin-Rang Yang, Mark A. Knepper;
Transcriptomes of major proximal tubule cell culture models.
J. Am. Soc. Nephrol. 32:86-97(2021)

Cross-references

Cell line collections (Providers)

ATCC; CRL-1571
BCRC; 60086
CLS; 305196
DSMZ; ACC-199
ECACC; 87012902
JCRB; IFO50480

Cell line databases/resources