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Cellosaurus MH7A (CVCL_0427)

[Text version]
Cell line name MH7A
Accession CVCL_0427
Resource Identification Initiative To cite this cell line use: MH7A (RRID:CVCL_0427)
Comments Population: Japanese.
Characteristics: Resveratrol induces apoptosis in MH7A cells (PubMed=20697895).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Synovium; UBERON=UBERON_0007616.
Cell type: Fibroblast-like synoviocyte; CL=CL_0002301.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line
STR profile Source(s): RCB=RCB1512

Markers:
AmelogeninX
CSF1PO12,14
D5S81812
D7S82010
D13S3178
D16S53910,11
TH016,9
TPOX8
vWA15,17

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Publications

PubMed=9832620; DOI=10.1093/oxfordjournals.jbchem.a022233
Keiji Miyazawa, Akio Mori, Hirokazu Okudaira;
Establishment and characterization of a novel human rheumatoid fibroblast-like synoviocyte line, MH7A, immortalized with SV40 T antigen.
J. Biochem. 124:1153-1162(1998)

PubMed=20697895; DOI=10.1007/s00296-010-1598-8; PMCID=PMC3253293
Hiroshi Nakayama, Takahiro Yaguchi, Shinichi Yoshiya, Tomoyuki Nishizaki;
Resveratrol induces apoptosis MH7A human rheumatoid arthritis synovial cells in a sirtuin 1-dependent manner.
Rheumatol. Int. 32:151-157(2012)

Cross-references
Cell line collections (Providers) RCB; RCB1512
Cell line databases/resources CLO; CLO_0050142
MCCL; MCC:0000324
Anatomy/cell type resources BTO; BTO_0003437
Biological sample resources BioSample; SAMN03472146
Encyclopedic resources Wikidata; Q54905531
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number20