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Cellosaurus MCF7/BUS (CVCL_0413)

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Cell line name MCF7/BUS
Synonyms MCF-7/BUS; MCF-7 BUS; MCF7 BUS
Accession CVCL_0413
Resource Identification Initiative To cite this cell line use: MCF7/BUS (RRID:CVCL_0413)
Comments Population: Caucasian.
Characteristics: Shows a very high proliferative response to estradiol-17beta (PubMed=7498097).
Doubling time: 32 +- 1.7 hours (Note=In 10% FBS-DME), 46 +- 3.0 hours (Note=In CDHS-PhR DME) (PubMed=7498097).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
STR profile Source(s): Millipore=SCC276

Markers:
AmelogeninX
CSF1PO10
D3S135816
D5S81811,12
D7S8208,9
D8S117910,14
D13S31711
D16S53911,12
D18S5114
D21S1130
FGA23,24,25
Penta D12
Penta E7,12
TH016
TPOX9,12
vWA14,15

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Publications

PubMed=7498097; DOI=10.1289/ehp.95103844; PMCID=PMC1519213
Mercedes Villalobos, Nicolas Olea, Jose Antonio Brotons, Maria Fatima Olea-Serrano, J. Mariano Ruiz de Almodovar, Vicente Pedraza;
The E-screen assay: a comparison of different MCF7 cell stocks.
Environ. Health Perspect. 103:844-850(1995)

Cross-references
Cell line collections (Providers) Millipore; SCC276
Cell line databases/resources MCCL; MCC:0000309
cancercelllines; CVCL_0413
Encyclopedic resources Wikidata; Q54904465
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number24