Cellosaurus logo
expasy logo

Cellosaurus M7TS90 (CVCL_0404)

[Text][XML][JSON]
Cell line name M7TS90
Accession CVCL_0404
Resource Identification Initiative To cite this cell line use: M7TS90 (RRID:CVCL_0404)
Comments Population: Caucasian.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=11980662
Daniel B. Longley, John Boyer, Wendy L. Allen, Tariq Latif, Paul R. Ferguson, Pamela J. Maxwell, Ultan McDermott, Maria Lynch, Denis Paul Harkin, Patrick Gerard Johnston;
The role of thymidylate synthase induction in modulating p53-regulated gene expression in response to 5-fluorouracil and antifolates.
Cancer Res. 62:2644-2649(2002)

Cross-references
Cell line databases/resources MCCL; MCC:0000298
cancercelllines; CVCL_0404
Encyclopedic resources Wikidata; Q54903649
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number20