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Cellosaurus K562/A02 (CVCL_0368)

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Cell line name K562/A02
Accession CVCL_0368
Resource Identification Initiative To cite this cell line use: K562/A02 (RRID:CVCL_0368)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_28748; Doxorubicin (Adriablastin; Adriamycin).
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=7668104
Chun-Zheng Yang, Feng-Jun Luan, Dong-Sheng Xiong, Bin-Ren Liu, Yuan-Fu Xu, Kong-Shu Gu;
Multidrug resistance in leukemic cell line K562/A02 induced by doxorubicin.
Zhongguo Yao Li Xue Bao 16:333-337(1995)

Cross-references
Cell line databases/resources MCCL; MCC:0000262
Chemistry resources ChEMBL-Cells; CHEMBL4295416
ChEMBL-Targets; CHEMBL4296448
PubChem_Cell_line; CVCL_0368
Encyclopedic resources Wikidata; Q54899401
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number23