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Cellosaurus HO-23 (CVCL_0309)

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Cell line name HO-23
Synonyms HO23
Accession CVCL_0309
Resource Identification Initiative To cite this cell line use: HO-23 (RRID:CVCL_0309)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
Genetic integration: Method=Transfection; Gene=MGI; MGI:98834; Trp53 (Note=With p.Ala132Val).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Ovary, ovarian follicle, granulosa cell layer; UBERON=UBERON_0005170.
Cell type: Granulosa cell; CL=CL_0000501.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=9794480; DOI=10.1210/endo.139.11.6279
Kumiko Hosokawa, Ada Dantes, Carolina Schere-Levy, Amihai Barash, Yoshio Yoshida, Fumikazu Kotsuji, Israel Vlodavsky, Abraham Amsterdam;
Induction of Ad4BP/SF-1, steroidogenic acute regulatory protein, and cytochrome P450scc enzyme system expression in newly established human granulosa cell lines.
Endocrinology 139:4679-4687(1998)

PubMed=15541573; DOI=10.1016/j.mce.2004.04.018
Jon Christopher Havelock, William E. Rainey, Bruce R. Carr;
Ovarian granulosa cell lines.
Mol. Cell. Endocrinol. 228:67-78(2004)

Cross-references
Cell line databases/resources MCCL; MCC:0000202
Encyclopedic resources Wikidata; Q54890088
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number13