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Cellosaurus GI-101A (CVCL_0278)

[Text version]
Cell line name GI-101A
Synonyms GI101A; GI 101A; GI-101; GI 101; GI101
Accession CVCL_0278
Secondary accession CVCL_5214
Resource Identification Initiative To cite this cell line use: GI-101A (RRID:CVCL_0278)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12420.
Characteristics: Established from a athymic mice xenograft.
Doubling time: 36 hours (Note=In a medium with 10% serum) (PubMed=14598885).
Omics: Transcriptomics; miRNA profiling; Microarray.
Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Disease Breast carcinoma (NCIt: C4872)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_D255 (GILM1)
Sex of cell Female
Age at sampling 57Y
Category Cancer cell line
Web pages Info; Pawefish; -; https://www.cellosaurus.org/pawefish/BreastCellLineDescriptions/GI%20101.html
Publications

PubMed=10328849; DOI=10.1006/cbir.1998.0269
Morrissey J.J., Raney S.
A metastatic breast tumor cell line, GI-101A, is estrogen receptor positive and responsive to estrogen but resistant to tamoxifen.
Cell Biol. Int. 22:413-419(1998)

Patent=US6037520
Raney S., Emma D.A., Hurst J.M.
Human breast carcinoma cell line capable of production of a spontaneously metastasizing tumor in animals for use in anticancer drug testing.
Patent number US6037520, 14-Mar-2000

PubMed=12800145; DOI=10.1002/gcc.10218
Adelaide J., Huang H.-E., Murati A., Alsop A.E., Orsetti B., Mozziconacci M.-J., Popovici C., Ginestier C., Letessier A., Basset C., Courtay-Cahen C., Jacquemier J., Theillet C., Birnbaum D., Edwards P.A.W., Chaffanet M.
A recurrent chromosome translocation breakpoint in breast and pancreatic cancer cell lines targets the neuregulin/NRG1 gene.
Genes Chromosomes Cancer 37:333-345(2003)

PubMed=14598885; DOI=10.1023/A:1025837631179
Lev D.C., Kiriakova G., Price J.E.
Selection of more aggressive variants of the GI101A human breast cancer cell line: a model for analyzing the metastatic phenotype of breast cancer.
Clin. Exp. Metastasis 20:515-523(2003)

Cross-references
Cell line databases/resources MCCL; MCC:0000169
cancercelllines; CVCL_0278
Encyclopedic resources Wikidata; Q54835803
Gene expression databases GEO; GSM217569
GEO; GSM219931
Polymorphism and mutation databases Cosmic; 687469
Progenetix; CVCL_0278
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number26