Cellosaurus cell line Fa2N-4 (CVCL

Cellosaurus Fa2N-4 (CVCL_0267)

Cross-references
Cell line name	Fa2N-4
Synonyms	Fa2N4
Accession	CVCL_0267
Resource Identification Initiative	To cite this cell line use: Fa2N-4 (RRID:CVCL_0267)
Comments	Group: Patented cell line. From: MultiCell Technologies, Inc.; Woonsocket; USA. Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-5566. Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Liver; UBERON=UBERON_0002107. Cell type: Hepatocyte; CL=CL_0000182.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	12Y
Category	Transformed cell line
Publications	PubMed=14722322; DOI=10.1124/jpet.103.061713 Jessica B. Mills, Kelly A. Rose, Nalini Sadagopan, Jasminder Sahi, Sonia M.F. de Morais; Induction of drug metabolism enzymes and MDR1 using a novel human hepatocyte cell line. J. Pharmacol. Exp. Ther. 309:303-309(2004) PubMed=18332078; DOI=10.1124/dmd.108.020677 Niresh Hariparsad, Brian A. Carr, Raymond Evers, Xiao-Yan Chu; Comparison of immortalized Fa2N-4 cells and human hepatocytes as in vitro models for cytochrome P450 induction. Drug Metab. Dispos. 36:1046-1055(2008) Patent=US7566567 Jin Liu, Ronald A. Faris; Immortalized hepatocytes. Patent number US7566567, 28-Jul-2009
Cell line databases/resources	CLO; CLO_0037255 MCCL; MCC:0000158
Encyclopedic resources	Wikidata; Q54833201
Entry history
Entry creation	04-Apr-2012
Last entry update	14-Aug-2025
Version number	16