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Cellosaurus EL4 (CVCL_0255)

[Text version]
Cell line name EL4
Synonyms EL-4; EL 4; E.L.4
Accession CVCL_0255
Resource Identification Initiative To cite this cell line use: EL4 (RRID:CVCL_0255)
Comments Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981).
Doubling time: ~15-20 hours (DSMZ=ACC-831); ~14 hours (Note=Lot 10262015), ~12 hours (Note=Lot 02052018) (JCRB=JCRB1350).
Transformant: ChEBI; CHEBI_254496; 7,12-dimethyltetraphene (DMBA; dimethylbenzanthracene).
Omics: Proteomics; HLA class I peptidome.
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: T-cell; CL=CL_0000084.
Disease Mouse precursor T cell lymphoblastic lymphoma/leukemia (NCIt: C21925)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6N.
Hierarchy Children:
CVCL_3505 (E.G7-OVA)CVCL_A0DM (EL-4 6.1)CVCL_E3E7 (EL-4/cCD20)
CVCL_8603 (EL-4ad)CVCL_B6PH (EL4-B7-2)CVCL_E8H0 (EL4-hCD19-LZ)
CVCL_E6BL (EL4-hCD20-LZ)CVCL_A4BN (EL4-Luc2 [ATCC])CVCL_5J22 (EL4-luc2 [Caliper])
CVCL_F943 (EL4-TK)CVCL_A0PX (EL4-Zbtb1 KO)CVCL_B6PK (EL4/E2)
CVCL_3818 (EL4.BU)CVCL_5680 (EL4.BU.1.OUAr.1.1)CVCL_0256 (EL4.E1)
CVCL_5681 (EL4.IL-2)CVCL_B6PG (EL4B7-1)CVCL_B6PL (EL4B7-2)
CVCL_E1JT (HyCyte EL4 KO-mErlin1)CVCL_E1JU (HyCyte EL4 KO-mTmem176b)CVCL_E3H6 (HyCyte EL4-Luc)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Web pages Info; COPE; -; http://www.cells-talk.com/index.php/page/copelibrary?key=EL4
Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/e/cell-lines-detail-141.html
Provider; Altogen; Xenograft model; https://altogenlabs.com/xenograft-models/lymphoma-xenograft/el4-xenograft-model/
Publications

PubMed=14801344; DOI=10.1038/bjc.1950.36; PMCID=PMC2007731
Peter Alfred Gorer;
Studies in antibody response of mice to tumour inoculation.
Br. J. Cancer 4:372-379(1950)

PubMed=4867923
John Patrick Glynn Jr., James L. McCoy, Alex Fefer;
Cross-resistance to the transplantation of syngeneic Friend, Moloney, and Rauscher virus-induced tumors.
Cancer Res. 28:434-439(1968)

PubMed=4099030; DOI=10.1126/science.171.3966.75
Behzad Mohit, Kang Fan;
Hybrid cell line from a cloned immunoglobulin-producing mouse myeloma and a nonproducing mouse lymphoma.
Science 171:75-77(1971)

PubMed=30084848; DOI=10.1038/sdata.2018.157; PMCID=PMC6080492
Heiko Schuster, Wen-Guang Shao, Tobias Weiss, Patrick G.A. Pedrioli, Patrick Roth, Michael Weller, David S. Campbell, Eric W. Deutsch, Robert L. Moritz, Oliver Planz, Hans-Georg Rammensee ...Show all 13 authors... , Rudolf Aebersold, Etienne Caron; Show fewer authors
A tissue-based draft map of the murine MHC class I immunopeptidome.
Sci. Data 5:180157.1-180157.11(2018)

Cross-references
Cell line collections (Providers) ATCC; TIB-39
BCRC; 60179
CCTCC; GDC0136
CLS; 300653
DSMZ; ACC-831
ECACC; 85023105
JCRB; IFO50027 - Discontinued
JCRB; JCRB1350
KCB; KCB 2013027YJ
KCLB; 40039
NCBI_Iran; C114
RCB; RCB1641
TKG; TKG 0150
Cell line databases/resources CLO; CLO_0002913
CLO; CLO_0050166
MCCL; MCC:0000146
CLDB; cl1158
CLDB; cl1159
CLDB; cl1160
CCRID; 1101MOU-PUMC000136
CCRID; 3101MOUTCM41
CCRID; 4201MOU-CCTCC00136
DSMZCellDive; ACC-831
Lonza; 760
Anatomy/cell type resources BTO; BTO_0003432
Chemistry resources ChEMBL-Cells; CHEMBL3308380
ChEMBL-Targets; CHEMBL614293
PubChem_Cell_line; CVCL_0255
Encyclopedic resources Wikidata; Q54832230
Experimental variables resources EFO; EFO_0022736
Proteomic databases PRIDE; PXD008733
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number32