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Cellosaurus CATH.a (CVCL_0204)

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Cell line name CATH.a
Synonyms Cath.a; CATH-a; CATHa; Central Adrenergic TH-expressing a
Accession CVCL_0204
Resource Identification Initiative To cite this cell line use: CATH.a (RRID:CVCL_0204)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11179.
Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Cell type: Neuron; CL=CL_0000540.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6 x DBA/2 rTH promoter-TAg transgenic.
Hierarchy Children:
CVCL_0199 (CAD)
Originate from same individual CVCL_E3FK ! CATH.b
Sex of cell Male
Age at sampling Embryo
Category Transformed cell line
Web pages Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/c/cell-lines-detail-118.html
Publications

PubMed=7680068; DOI=10.1523/JNEUROSCI.13-03-01280.1993; PMCID=PMC6576599
Chitra Suri, Brenda P. Fung, Arthur Steven Tischler, Dona M. Chikaraishi;
Catecholaminergic cell lines from the brain and adrenal glands of tyrosine hydroxylase-SV40 T antigen transgenic mice.
J. Neurosci. 13:1280-1291(1993)

PubMed=7665571; DOI=10.1074/jbc.270.37.21579
Meredith A. Lazaroff, Swati Patankar, Sung Ok Yoon, Dona M. Chikaraishi;
The cyclic AMP response element directs tyrosine hydroxylase expression in catecholaminergic central and peripheral nervous system cell lines from transgenic mice.
J. Biol. Chem. 270:21579-21589(1995)

Patent=US5591626
Dona M. Chikaraishi;
Expression of a target gene in transgenic mammals with 5' flanking sequences of the rat tyrosine hydroxylase gene.
Patent number US5591626, 07-Jan-1997

PubMed=9006967; DOI=10.1523/JNEUROSCI.17-04-01217.1997; PMCID=PMC6793738
Yan-Ping Qi, James K.-T. Wang, Michael McMillian, Dona M. Chikaraishi;
Characterization of a CNS cell line, CAD, in which morphological differentiation is initiated by serum deprivation.
J. Neurosci. 17:1217-1225(1997)

Cross-references
Cell line collections (Providers) ATCC; CRL-3595
ATCC; CRL-11179 - Discontinued
KCB; KCB 2014010YJ
Cell line databases/resources CLO; CLO_0002207
MCCL; MCC:0000093
Anatomy/cell type resources BTO; BTO_0005820
Encyclopedic resources Wikidata; Q54808629
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number20