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Cellosaurus AlphaT3-1 (CVCL_0149)

[Text version]
Cell line name AlphaT3-1
Synonyms AlphaT31; alphaT3-1; alpha T3-1; alpha-T3-1; aT3-1
Accession CVCL_0149
Resource Identification Initiative To cite this cell line use: AlphaT3-1 (RRID:CVCL_0149)
Comments Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; SV40 large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Pituitary gland; UBERON=UBERON_0000007.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6 x BALB/c transgenic.
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=1704103; DOI=10.1210/mend-4-4-597
Windle J.J., Weiner R.I., Mellon P.L.
Cell lines of the pituitary gonadotrope lineage derived by targeted oncogenesis in transgenic mice.
Mol. Endocrinol. 4:597-603(1990)

PubMed=8898243; DOI=10.1242/dev.122.10.3319
Alarid E.T., Windle J.J., Whyte D.B., Mellon P.L.
Immortalization of pituitary cells at discrete stages of development by directed oncogenesis in transgenic mice.
Development 122:3319-3329(1996)

PubMed=15541569; DOI=10.1016/j.mce.2004.07.018
Ooi G.T., Tawadros N., Escalona R.M.
Pituitary cell lines and their endocrine applications.
Mol. Cell. Endocrinol. 228:1-21(2004)

PubMed=31020055; DOI=10.1210/js.2019-00064; PMCID=PMC6469952
Ruf-Zamojski F., Ge Y.-C., Pincas H., Shan J.-D., Song Y.-H., Hines N., Kelley K., Montagna C., Nair P., Toufaily C., Bernard D.J., Mellon P.L., Nair V., Turgeon J.L., Sealfon S.C.
Cytogenetic, genomic, and functional characterization of pituitary gonadotrope cell lines.
J. Endocr. Soc. 3:902-920(2019)

Cross-references
Cell line databases/resources MCCL; MCC:0000042
Anatomy/cell type resources BTO; BTO_0003566
Encyclopedic resources Wikidata; Q54749261
Experimental variables resources EFO; EFO_0022819
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number16