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Cellosaurus AML12 (CVCL_0140)

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Cell line name AML12
Synonyms AML-12; AML 12; Alpha Mouse Liver 12
Accession CVCL_0140
Resource Identification Initiative To cite this cell line use: AML12 (RRID:CVCL_0140)
Comments Doubling time: 37 hours (PubMed=7904757); 36-48 hours (Hysigen=TCM-C709).
Genetic integration: Method=Transgenic mouse; Gene=HGNC; HGNC:11765; TGFA.
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Hepatocyte; CL=CL_0000182.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: CD-1 MT42 transgenic.
Hierarchy Children:
CVCL_D6AU (HyCyte AML12 KO-mIgf2)CVCL_F1MM (HyCyte AML12 KO-mKat7)CVCL_E1J5 (HyCyte AML12 KO-mNsun6)
CVCL_F1MN (HyCyte AML12 KO-mRtn4)CVCL_F1MP (HyCyte AML12 KO-mSelenoo)CVCL_F1MQ (HyCyte AML12 KO-mTrim14)
CVCL_E3GR (HyCyte AML12-Luc)CVCL_D8DT (Ubigene AML12 Atp7b KO)CVCL_D8DU (Ubigene AML12 Cs KO)
CVCL_D8DV (Ubigene AML12 Faah KO)CVCL_D8DW (Ubigene AML12 Fasn KO)CVCL_D8DX (Ubigene AML12 Ldlr KO)
Sex of cell Male
Age at sampling 5M
Category Spontaneously immortalized cell line
STR profile Source(s): Ubigene=YC-D022; Hysigen=TCM-C709

Markers:
Mouse STR 1-111
Mouse STR 1-213
Mouse STR 2-19
Mouse STR 3-214
Mouse STR 4-220.3
Mouse STR 5-514,15
Mouse STR 6-416
Mouse STR 6-712
Mouse STR 7-116.2
Mouse STR 8-114,15
Mouse STR 11-218,19
Mouse STR 12-119
Mouse STR 13-115.1
Mouse STR 15-321.3
Mouse STR 17-214,15
Mouse STR 18-321
Mouse STR 19-213
Mouse STR X-126

Run an STR similarity search on this cell line
Web pages Info; ATCC; -; https://www.atcc.org/en/support/technical-support/faqs/morphology-of-atcc-crl-2254
Publications

PubMed=7904757; DOI=10.1073/pnas.91.2.674; PMCID=PMC43011
Justina C. Wu, Glenn T. Merlino, Nelson Fausto;
Establishment and characterization of differentiated, nontransformed hepatocyte cell lines derived from mice transgenic for transforming growth factor alpha.
Proc. Natl. Acad. Sci. U.S.A. 91:674-678(1994)

Cross-references
Cell line collections (Providers) ATCC; CRL-2254
BCRC; 60326
BCRJ; 0354
CLS; 300643
Hysigen; TCM-C709
IZSLER; BS CL 161
Ubigene; YC-D022
Cell line databases/resources CLO; CLO_0001716
MCCL; MCC:0000033
CCRID; 3101MOUSCSP550
Anatomy/cell type resources BTO; BTO_0003449
Encyclopedic resources Wikidata; Q54749800
Gene expression databases GEO; GSE87156
GEO; GSM294842
GEO; GSM296415
GEO; GSM296416
GEO; GSM296417
GEO; GSM1374079
GEO; GSM1374080
GEO; GSM1374081
GEO; GSM1374082
GEO; GSM1374083
GEO; GSM1374084
Entry history
Entry creation04-Apr-2012
Last entry update31-Mar-2026
Version number23