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Cellosaurus 2008/C13*5.25 (CVCL_0114)

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Cell line name 2008/C13*5.25
Synonyms 2008/C13_5_25; 2008/c13*5.25; OV 2008/C13*5.25; OV2008/C13; 2008C13; 2008 C-13; C13; 2008/C13.R; ME180C13
Accession CVCL_0114
Resource Identification Initiative To cite this cell line use: 2008/C13*5.25 (RRID:CVCL_0114)
Comments Problematic cell line: Contaminated. Parent cell line (OV-2008) has been shown to be a ME-180 derivative (PubMed=22710073).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00522.
Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
Transformant: NCBI_TaxID; 45240; Human papillomavirus type 68 (HPV68).
Omics: Proteomics.
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Omentum; UBERON=UBERON_0003688.
Sequence variations
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Human papillomavirus-related cervical squamous cell carcinoma (NCIt: C27676)
Squamous cell carcinoma of the cervix uteri (ORDO: Orphanet_213767)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0473 (OV-2008)
Sex of cell Female
Age at sampling 66Y
Category Cancer cell line
STR profile Source(s): PubMed=22710073

Markers:
AmelogeninX
CSF1PO11
D2S133818
D3S135816
D5S81812
D7S8209
D8S117914
D13S31711,12
D16S53912,13
D18S5112
D19S43315.2
D21S1130,31
FGA23
TH018,9.3
TPOX8,10
vWA15,17

Run an STR similarity search on this cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017; PMCID=PMC3432677
Christopher T. Korch, Monique A. Spillman, Twila A. Jackson, Britta M. Jacobsen, Susan K. Murphy, Bruce Arthur Lessey, Virgil Craig Jordan, Andrew Peter Bradford;
DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination.
Gynecol. Oncol. 127:241-248(2012)

PubMed=27561551; DOI=10.1038/ncomms12645; PMCID=PMC5007461
Fabian Coscia, Karen M. Watters, Marion Curtis, Mark A. Eckert, Chun-Yi Chiang, Stefka Tyanova, Anthony Montag, Ricardo R. Lastra, Ernst Robert Lengyel, Matthias Mann;
Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status.
Nat. Commun. 7:12645.1-12645.14(2016)

Cross-references
Cell line collections (Providers) NCBI_Iran; C446
Cell line databases/resources MCCL; MCC:0000005
cancercelllines; CVCL_0114
Anatomy/cell type resources BTO; BTO_0003989
Biological sample resources BioSample; SAMN03151842
BioSample; SAMN06481105
Chemistry resources ChEMBL-Cells; CHEMBL3308686
ChEMBL-Targets; CHEMBL614863
PubChem_Cell_line; CVCL_0114
Encyclopedic resources Wikidata; Q54583043
Gene expression databases GEO; GSM711717
GEO; GSM851911
Polymorphism and mutation databases Cosmic; 948294
Cosmic; 1479983
Proteomic databases PRIDE; PXD003668
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number32