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Cellosaurus Karpas-707 (CVCL_0010)

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Cell line name Karpas-707
Synonyms KARPAS-707; Karpas 707; KARPAS 707; Karpas707
Accession CVCL_0010
Resource Identification Initiative To cite this cell line use: Karpas-707 (RRID:CVCL_0010)
Comments Part of: Human Protein Atlas, Cell Atlas panel.
Characteristics: Produces Ig lambda.
Doubling time: 35 hours (PubMed=11172031).
Omics: Proteomics; Expression; Large antibody panel staining analysis.
Omics: Transcriptomics; RNAseq.
Caution: PubMed=17254797 reports a totally different STR profile which we believe to be erroneous. It is: CSF1PO=10,13; D13S317=11; D16S539=12; D18S51=16,18; D21S11=30,31; D3S1358=15; D5S818=11; D7S820=8; D8S1179=12,13; FGA=18,26; TH01=6,10; TPOX=8; vWA=17,18.
Misspelling: CARPAS 707; PubMed=17254797.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Plasma cell; CL=CL_0000786.
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_9552 (Karpas-707H)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
STR profile Source(s): ECACC=22110801

Markers:
AmelogeninX
CSF1PO11,13
D3S135814,17
D5S81811
D7S82010
D8S117911,12
D13S3179
D16S53911,12
D18S5111,15
FGA18,23
Penta D9,10
Penta E9,10
TH019
TPOX9,11
vWA20,21

Run an STR similarity search on this cell line
Web pages Info; HPA; -; https://www.proteinatlas.org/learn/cellines
Publications

PubMed=7079750; DOI=10.1126/science.7079750
Abraham Karpas, Patricia E. Fischer, David Swirsky;
Human myeloma cell line carrying a Philadelphia chromosome.
Science 216:997-999(1982)

DOI=10.1007/978-1-4613-2823-0_29
Abraham Karpas;
Viruses and human leukemia in vitro.
(In book chapter) Human leukemia. Cytochemical and ultrastructural techniques in diagnosis and research. Developments in Oncology, Vol. 14; Polliack, Aaron (eds.); pp.495-526; Martinus Nijhoff Publishing; Boston; USA (1984)

PubMed=3332852; DOI=10.1016/S0950-3536(87)80037-9
Armand Keating;
Ph positive CML cell lines.
Baillieres Clin. Haematol. 1:1021-1029(1987)

DOI=10.1007/0-306-46877-8_4
Helena Jernberg-Wiklund, Kenneth Nilsson;
Multiple myeloma cell lines.
(In book chapter) Human cell culture. Vol. 3. Cancer cell lines part 3; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.81-155; Kluwer Academic Publishers; New York; USA (2000)

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Hans Gunther Drexler, Yoshinobu Matsuo;
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=11172031; DOI=10.1073/pnas.98.4.1799; PMCID=PMC29337
Abraham Karpas, Alla Dremucheva, Barbara H. Czepulkowski;
A human myeloma cell line suitable for the generation of human monoclonal antibodies.
Proc. Natl. Acad. Sci. U.S.A. 98:1799-1804(2001)

PubMed=16957166; DOI=10.1369/jhc.6A7001.2006; PMCID=PMC3958123
Ann-Catrin Andersson, Sara Stromberg, Helena Backvall, Caroline Kampf, Mathias Uhlen, Kenneth Wester, Fredrik Ponten;
Analysis of protein expression in cell microarrays: a tool for antibody-based proteomics.
J. Histochem. Cytochem. 54:1413-1423(2006)

PubMed=17254797; DOI=10.1016/j.biologicals.2006.10.001
Shahram Azari, Nahid Ahmadi, Mahmood Jeddi-Tehrani, Fazel Shokri;
Profiling and authentication of human cell lines using short tandem repeat (STR) loci: report from the National Cell Bank of Iran.
Biologicals 35:195-202(2007)

PubMed=23074853; DOI=10.1134/S1990519X12050136
Victoria I. Turilova, Tatyana Dmitriyevna Smirnova;
Karyotypic variability of human myeloma cell lines.
Tsitologiia 54:621-636(2012)

Cross-references
Cell line collections (Providers) ECACC; 22110801
NCBI_Iran; C505
Encyclopedic resources Wikidata; Q54899503
Gene expression databases GEO; GSM7701422
GEO; GSM7701423
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number24