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Cellosaurus SfSWT-7 (CVCL_C3MG)

[Text version]
Cell line name SfSWT-7
Accession CVCL_C3MG
Resource Identification Initiative To cite this cell line use: SfSWT-7 (RRID:CVCL_C3MG)
Comments Group: Insect cell line.
Group: Patented cell line.
Group: Recombinant protein production insect cell line.
Characteristics: Can produce sulfated complex N-glycans. The expression of the carbohydrate modidying enzymes is under the transcriptional control of baculovirus immediate early 1 (ie1) promoter and homologous region 5 (hr5) enhancer elements.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 7045; MGAT2.
Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:1891160; Chst2.
Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:2685834; Gal3st2.
Genetic integration: Method=Transfection/transduction; Gene=VGNC; 26388; Bovine B4GALT1.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Species of origin Spodoptera frugiperda (Fall armyworm) (NCBI Taxonomy: 7108)
Hierarchy Parent: CVCL_4U10 (Sf900+)
Sex of cell Female
Age at sampling Pupal stage
Category Spontaneously immortalized cell line
Publications

PubMed=23848607; DOI=10.1021/pr400329k; PMCID=PMC3800089
An Y.-M., Rininger J.A., Jarvis D.L., Jing X.-H., Ye Z.-P., Aumiller J.J., Eichelberger M.C., Cipollo J.F.
Comparative glycomics analysis of influenza Hemagglutinin (H5N1) produced in vaccine relevant cell platforms.
J. Proteome Res. 12:3707-3720(2013)

Patent=US9045778
Jarvis D.L.
An insect cell line for production of recombinant glycoproteins with sulfated complex N-glycans.
Patent number US9045778, 02-Jun-2015

Cross-references
Encyclopedic resources Wikidata; Q116050498
Entry history
Entry creation15-Dec-2022
Last entry update10-Sep-2024
Version number5