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Cellosaurus Sf900+ (CVCL_4U10)

[Text version]
Cell line name Sf900+
Synonyms expresSF+; expressSF+; express SF+; Express Sf+; Sf+
Accession CVCL_4U10
Resource Identification Initiative To cite this cell line use: Sf900+ (RRID:CVCL_4U10)
Comments Group: Insect cell line.
Group: Patented cell line.
Group: Recombinant protein production insect cell line.
Group: Vaccine production cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12579.
Biotechnology: Used for the production of the porcine circovirus type 2 (PCV2) vaccine CircoFLEX. Used to produce the PCV2 ORF2 capsid protein (PubMed=29133148).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Species of origin Spodoptera frugiperda (Fall armyworm) (NCBI Taxonomy: 7108)
Hierarchy Parent: CVCL_0549 (Sf9)
Children:
CVCL_C3MG (SfSWT-7)
Sex of cell Female
Age at sampling Pupal stage
Category Spontaneously immortalized cell line
Publications

Patent=US6103526
Smith G.E., Foellmer H.G., Knell J., DeBartolomeis J., Voznesensky A.I.
Spodoptera frugiperda single cell suspension cell line in serum-free media, methods of producing and using.
Patent number US6103526, 15-Aug-2000

PubMed=18304705; DOI=10.1016/j.vaccine.2007.11.053
Fachinger V., Bischoff R., Ben Jedidia S., Saalmuller A., Elbers K.
The effect of vaccination against porcine circovirus type 2 in pigs suffering from porcine respiratory disease complex.
Vaccine 26:1488-1499(2008)

PubMed=22265860; DOI=10.1016/j.vaccine.2012.01.016; PMCID=PMC7115678
Cox M.M.J.
Recombinant protein vaccines produced in insect cells.
Vaccine 30:1759-1766(2012)

PubMed=23848607; DOI=10.1021/pr400329k; PMCID=PMC3800089
An Y.-M., Rininger J.A., Jarvis D.L., Jing X.-H., Ye Z.-P., Aumiller J.J., Eichelberger M.C., Cipollo J.F.
Comparative glycomics analysis of influenza Hemagglutinin (H5N1) produced in vaccine relevant cell platforms.
J. Proteome Res. 12:3707-3720(2013)

PubMed=29133148; DOI=10.1016/j.pep.2017.11.002; PMCID=PMC5826799
Geisler C., Jarvis D.L.
Adventitious viruses in insect cell lines used for recombinant protein expression.
Protein Expr. Purif. 144:25-32(2018)

Cross-references
Encyclopedic resources Wikidata; Q54953005
Entry history
Entry creation22-Sep-2015
Last entry update29-Jun-2023
Version number11