Molecular Cytogenetics of Common Epithelial Cancers > Breast Carcinoma cell lines > SK-BR-7

SK-BR-7   [Cellosaurus entry CVCL_5218]

Breast Carcinoma Cell Line

Description A hypodiploid cell line demonstrating net loss of chromosomes. Derived by Fogh and Trempe (1975), who derived SK-BR-3, but subsequent to their paper, and obtained from Dr Mike O'Hare.
Notable Features Translocations involve chromosomes 1, 4, 9, 14, 15 and 19.
Representative SKY Karyotype
43(38-44).1x1, der(1)t(1;4), der(?)t(1;19), 2x2, 3x2, der(15?)t(4;15), der(4)t(4;9), 5x2, 6x2, 7x2, 8x2, 9x1, 10x2, 11x2, 12x2, 13x2, 14x1, der(9)t(9;14), 15x1, 16x2, 17x2, 18x2, 19x1, 20x2, 21x2, 22x1, Xx2 cp[10]
CGH results  




Breast Cell Lines