Molecular Cytogenetics of Common Epithelial Cancers > Breast Carcinoma cell lines > PMC42

PMC42   [Cellosaurus entry CVCL_5215]

Breast Carcinoma Cell Line

Description A highly rearranged, near tetraploid cell line derived by Whitehead R et al., 1983 and obtained from Dr Mike O'Hare.
Notable Features Translocations involve 2, 3, 7, 8, 9, 10, 11, 14, 15, 16, 17, 18, 19 and X. Deletions were detected on chromosomes 1, 2, 3, 8 and 11.
Representative SKY Karyotype
57(52-67).1x2, del(1)(q?), 2x1, del(2)(p?), 3x1, del(3)(p?), der(3)t(3;11), 4x2, 5x4, 6x2, 7x3, der(7)t(7;10), 8x2, del(8)(q?), 9x2, 10x2, 11x1, del(11)(p?), der(11)t(9;11)x2, 12x3, 13x2, 14x2, der(14)t(10;14), 15x3, 16x2, der(16)t(16;17), 17x2, 18x2, der(?)t(8;18), 19x1, der(19)t(2;19)x2, der(19)t(15;19), 20x4, 21x2, 22x2, Xx1, der(X)t(X;2) cp[10]
CGH results  




Breast Cell Lines