Molecular Cytogenetics of Common Epithelial Cancers > Breast Carcinoma cell lines > MCF7

MCF7   [Cellosaurus entry CVCL_0031]

Breast Carcinoma Cell Line

Description A highly rearranged, near triploid cell line, held at the ATCC - obtained from Dr Mike O'Hare.
Notable Features Translocations involve all chromosomes, except 4. Several markers are very complex, having undergone multiple rearrangements. Deletions were detected on chromosomes 3 and 13.
Representative SKY Karyotype
65( 61-72) 1x1, der(1)t(X;1), 2x2, der(2)t(2;3)(q36;?), 3x2, del(3)(p?), der(3)t(3;6), 4x3, 5x3, der(5)t(5;13)(p12?;q22), 6x1, der(6)t(6;7), der(6)t(3;6), 7x1, der(7)t(1;19;7;6), der(7)t(7;19;7), 8x1, der(?)t(16;11;8;11;3), der(8)t(8;15), der(8?)t(8;12), der(8)t(8;16), 9x2, der(?)t(6;20;9;3), der(9)t(8;9), 10x2, der(10)t(7;10)(?;q22), 11x2, der(?)t(11;1;17;19;17), 12x3, der(19)t(12;19), del(13)(q?), der(13)t(13;15;11;16), der(13)t(13;14), der(13)t(13;16), 14x2, der(?)t(7;14), 15x2, der(16)t(15;16), 16x2, 17x1, der(17)t(3;17), 18x2, der(18)t(18;21), 19x1, der(19)t(7;19), 20x1, der(?)t(17;1;19;17;20), der(20)t(3;20;1;20;1;20), der(20)t(20;1;21?), 21x3, der(22)t(7;22), der(22)t(16;22), Xx2 cp[6]
CGH results  




Breast Cell Lines