Molecular Cytogenetics of Common Epithelial Cancers > Breast Carcinoma cell lines > HCC1599

HCC1599   [Cellosaurus entry CVCL_1256]

Breast Cancer Cell Line


A hypertriploid cell line from mammary gland; breast; duct; primary ductal carcinoma, held at ATCC, included in the Cancer Genome Project at the Sanger Institute.

Notable Features

Hypertriploid, extremely rearranged with 42 structural chromosome abnormalities, including one reciprocal translocation t (2;6), all chromosomes except 18 and X involved in rearrangements, losses involve chromosomes X, 2, 4q, 5q, 11, 14, 18, 20; gains inovolve 8 and 19.

Representative SKY Karyotype

karyotype with footnotes59(58-64) X, 1x1, der(1)t(1;6), der(1)t(8;1;4), der(1)t(3;1;6), der(2)t(2;6)(q36;p23)*, der(2)2;9;1), 3x1, der(3)t(3;15), dup(3), 4x1, der(4)t(14;4;17), der(4)del(4)(q1-qter), der(5)t(5;7), der(5)t(5;9), der(5)del(5)x2, der(6)t(2;6)(q36;p23)*, der(6;21)(p10;q10), der(6)t(1;6), der(6?)t(6;11;13), der(7)t(7;1;6), der(7)del(7)x2, 8x1, der(8)t(5;8); der(8?)t(8;1;7;1), der(8)t(8;21), 9x1, der(9)t(8;9)x2, 10x2, der(10)t(3:10)(?;q24-25), der(11)t(8;11), der(11)t(8;11), 12x1, der(12)t(6;12), der(12)t(5;12), i(13q), 14x0, 15x1, der(15)t(2;15), der(15)t(22;2;15), der(16)t(14;16), der(16)t(4;16), der(16)t(16;19;X), der(17)t(1;17), der(17)t(4;17), der(17)t(17;7?;1?;X), der(17)t(17;7?;19), 18x2, der(19)t(2;19)dup(19), der(19)t(11;19)dup(19), der(19)t(3;19)dup(19), 20x1, der(21)del(21), 22x2, der(22)t(20;22)




Breast Cancer Cell Lines