ID   ATL2ABR
AC   CVCL_ZT68
SY   Ataxia Telangiectasia-Like 2 Australia BRisbane
DR   Wikidata; Q98125520
RX   PubMed=16540636;
RX   PubMed=17347666;
RX   PubMed=25868131;
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DI   NCIt; C173403; Ataxia-oculomotor apraxia type 3
DI   ORDO; Orphanet_64753; Spinocerebellar ataxia with axonal neuropathy type 2
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_ZW04 ! PSF [Human AOA3 fibroblast]
CA   Transformed cell line
DT   Created: 02-07-20; Last updated: 29-06-23; Version: 4
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RX   PubMed=16540636; DOI=10.1158/0008-5472.CAN-05-3428;
RA   Gueven N., Becherel O.J., Birrell G.W., Chen P., DelSal G., Carney J.P.,
RA   Grattan-Smith P.J., Lavin M.F.;
RT   "Defective p53 response and apoptosis associated with an
RT   ataxia-telangiectasia-like phenotype.";
RL   Cancer Res. 66:2907-2912(2006).
//
RX   PubMed=17347666; DOI=10.1038/sj.cdd.4402116;
RA   Gueven N., Becherel O.J., Howe O., Chen P.-J., Haince J.-F.,
RA   Ouellet M.-E., Poirier G.G., Waterhouse N., Fusser M., Epe B.,
RA   Menissier-de Murcia J., de Murcia G., McGowan C.H., Parton R.G.,
RA   Mothersill C., Grattan-Smith P.J., Lavin M.F.;
RT   "A novel form of ataxia oculomotor apraxia characterized by oxidative
RT   stress and apoptosis resistance.";
RL   Cell Death Differ. 14:1149-1161(2007).
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RX   PubMed=25868131; DOI=10.1016/j.mrgentox.2015.03.012;
RA   Kobayashi J., Saito Y., Okui M., Miwa N., Komatsu K.;
RT   "Increased oxidative stress in AOA3 cells disturbs ATM-dependent DNA
RT   damage responses.";
RL   Mutat. Res. Genet. Toxicol. Environ. Mutagen. 782:42-50(2015).
//