ID   C5RO-hTERT
AC   CVCL_ZP37
SY   C5RO(tert)
DR   Wikidata; Q98125599
RX   PubMed=14690602;
RX   PubMed=17273966;
RX   PubMed=30165384;
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_ZP35 ! C5RO
SX   Female
AG   30Y
CA   Telomerase immortalized cell line
DT   Created: 02-07-20; Last updated: 19-12-24; Version: 7
//
RX   PubMed=14690602; DOI=10.1016/S1097-2765(03)00478-7;
RA   Zhu X.-D., Niedernhofer L.J., Kuster B., Mann M., Hoeijmakers J.H.J.,
RA   de Lange T.;
RT   "ERCC1/XPF removes the 3' overhang from uncapped telomeres and
RT   represses formation of telomeric DNA-containing double minute
RT   chromosomes.";
RL   Mol. Cell 12:1489-1498(2003).
//
RX   PubMed=17273966; DOI=10.1086/512486; PMCID=PMC1821117;
RA   Jaspers N.G.J., Raams A., Silengo M.C., Wijgers N., Niedernhofer L.J.,
RA   Robinson A.R., Giglia-Mari G., Hoogstraten D., Kleijer W.J.,
RA   Hoeijmakers J.H.J., Vermeulen W.;
RT   "First reported patient with human ERCC1 deficiency has
RT   cerebro-oculo-facio-skeletal syndrome with a mild defect in nucleotide
RT   excision repair and severe developmental failure.";
RL   Am. J. Hum. Genet. 80:457-466(2007).
//
RX   PubMed=30165384; DOI=10.1093/nar/gky774; PMCID=PMC6182131;
RA   Sabatella M., Theil A.F., Ribeiro-Silva C., Slyskova J., Thijssen K.,
RA   Voskamp C., Lans H., Vermeulen W.;
RT   "Repair protein persistence at DNA lesions characterizes XPF defect
RT   with Cockayne syndrome features.";
RL   Nucleic Acids Res. 46:9563-9577(2018).
//