ID   INS-1 832/3
AC   CVCL_ZL55
SY   INS-1 (832/3); 832/3
DR   Millipore; SCC208
DR   Wikidata; Q98126775
RX   PubMed=10868964;
RX   PubMed=18755687;
CC   Characteristics: Shows robust glucose-stimulated insulin secretion (GSIS) (Millipore=SCC208).
CC   Transfected with: HGNC; 6081; INS.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCIt; C17262; X-Ray.
CC   Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
CC   Cell type: Pancreatic beta cell; CL=CL_0000169.
CC   Breed/subspecies: NEDH.
DI   NCIt; C121566; Rat insulinoma
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
HI   CVCL_0352 ! INS-1
SX   Male
AG   666D
CA   Cancer cell line
DT   Created: 02-07-20; Last updated: 29-06-23; Version: 6
//
RX   PubMed=10868964; DOI=10.2337/diabetes.49.3.424;
RA   Hohmeier H.-E., Mulder H., Chen G.-X., Henkel-Rieger R., Prentki M.,
RA   Newgard C.B.;
RT   "Isolation of INS-1-derived cell lines with robust ATP-sensitive K+
RT   channel-dependent and -independent glucose-stimulated insulin
RT   secretion.";
RL   Diabetes 49:424-430(2000).
//
RX   PubMed=18755687; DOI=10.1074/jbc.M804665200;
RA   Ronnebaum S.M., Jensen M.V., Hohmeier H.-E., Burgess S.C., Zhou Y.-P.,
RA   Qian S., MacNeil D., Howard A., Thornberry N.A., Ilkayeva O., Lu D.-H.,
RA   Sherry A.D., Newgard C.B.;
RT   "Silencing of cytosolic or mitochondrial isoforms of malic enzyme has
RT   no effect on glucose-stimulated insulin secretion from rodent
RT   islets.";
RL   J. Biol. Chem. 283:28909-28917(2008).
//