DR   Wikidata; Q98127279
RX   PubMed=32402349;
CC   Virology: Highly susceptible to infection by porcine reproductive and respiratory syndrome virus type 2 (PRRSV-2) strains JXA1 and SD1 (PubMed=32402349).
CC   Transfected with: UniProtKB; E1AQW7; Pig CD163.
CC   Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [Note=pSV3-neo].
CC   Derived from site: In situ; Lung, alveolus; UBERON=UBERON_0002299.
CC   Cell type: Alveolar macrophage; CL=CL_0000583.
CC   Breed/subspecies: Landrace.
OX   NCBI_TaxID=9823; ! Sus scrofa (Pig)
HI   CVCL_0F14 ! IPAM 3D4/21
SX   Sex unspecified
AG   12W
CA   Transformed cell line
DT   Created: 02-07-20; Last updated: 05-10-23; Version: 9
RX   PubMed=32402349; DOI=10.1016/j.vetmic.2020.108690;
RA   Xu Y.-L., Wu S.-P., Li Y.-G., Sun F.-X., Wang Q.-J., Zhao Q., Yu J.,
RA   Tian F.-L., Wu J.-Q., Zhu R.-L., Peng J.;
RT   "A porcine alveolar macrophage cell line stably expressing CD163
RT   demonstrates virus replication and cytokine secretion characteristics
RT   similar to primary alveolar macrophages following PRRSV infection.";
RL   Vet. Microbiol. 244:108690.1-108690.6(2020).