ID   MOC2
AC   CVCL_ZD33
SY   Mouse Oral Cancer 2
DR   GEO; GSM1213080
DR   GEO; GSM1213081
DR   GEO; GSM1213082
DR   Kerafast; EWL002-FP
DR   Wikidata; Q98127271
RX   PubMed=22086849;
RX   PubMed=22434099;
RX   PubMed=24668645;
RX   PubMed=25729643;
CC   Characteristics: Agressive growth phenotype.
CC   Sequence variation: Mutation; MGI; MGI:96680; Kras; Simple; p.Gln61His (c.183A>T); Zygosity=Unspecified (PubMed=22086849).
CC   Sequence variation: Mutation; MGI; MGI:98834; Trp53; Simple; p.Glu225Ter; Zygosity=Unspecified (PubMed=24668645).
CC   Transformant: ChEBI; CHEBI:59032; 7,12-dimethyltetraphene (DMBA; dimethylbenzanthracene).
CC   Omics: Deep exome analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Breed/subspecies: C57BL/6 Cxcr3-/-.
ST   Source(s): Kerafast=EWL002-FP
ST   Mouse STR 12-1: 17
ST   Mouse STR 15-3: 22.3,23.3
ST   Mouse STR 18-3: 17
ST   Mouse STR 4-2: 20.3
ST   Mouse STR 5-5: 17
ST   Mouse STR 6-4: 18
ST   Mouse STR 6-7: 15
ST   Mouse STR X-1: 26
DI   NCIt; C23049; Squamous cell carcinoma of the mouse oral cavity
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
OI   CVCL_ZD38 ! MOC2LN
SX   Female
CA   Cancer cell line
DT   Created: 02-07-20; Last updated: 02-05-24; Version: 6
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RX   PubMed=22086849; DOI=10.1158/0008-5472.CAN-11-1831;
RA   Judd N.P., Winkler A.E., Murillo-Sauca O., Brotman J.J., Law J.H.,
RA   Lewis J.S. Jr., Dunn G.P., Bui J.D., Sunwoo J.B., Uppaluri R.;
RT   "ERK1/2 regulation of CD44 modulates oral cancer aggressiveness.";
RL   Cancer Res. 72:365-374(2012).
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RX   PubMed=22434099; DOI=10.1177/0194599812442037;
RA   Judd N.P., Allen C.T., Winkler A.E., Uppaluri R.;
RT   "Comparative analysis of tumor-infiltrating lymphocytes in a syngeneic
RT   mouse model of oral cancer.";
RL   Otolaryngol. Head Neck Surg. 147:493-500(2012).
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RX   PubMed=24668645; DOI=10.1158/1078-0432.CCR-14-0205;
RA   Onken M.D., Winkler A.E., Kanchi K.-L., Chalivendra V., Law J.H.,
RA   Rickert C.G., Kallogjeri D., Judd N.P., Dunn G.P., Piccirillo J.F.,
RA   Lewis J.S. Jr., Mardis E.R., Uppaluri R.;
RT   "A surprising cross-species conservation in the genomic landscape of
RT   mouse and human oral cancer identifies a transcriptional signature
RT   predicting metastatic disease.";
RL   Clin. Cancer Res. 20:2873-2884(2014).
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RX   PubMed=25729643; DOI=10.1016/j.gdata.2014.11.006;
RA   Chalivendra V., Kanchi K.-L., Onken M.D., Winkler A.E., Mardis E.R.,
RA   Uppaluri R.;
RT   "Genomic analysis to define molecular basis of aggressiveness in a
RT   mouse model of oral cancer.";
RL   Genomics Data 3:61-62(2015).
//