ID   C8-MEF
AC   CVCL_Z847
SY   C8 MEF; C8
DR   BTO; BTO_0005560
DR   Wikidata; Q54808246
RX   PubMed=8134344;
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P03255; Adenovirus 5 E1A protein.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5 (Note=E1A).
CC   Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   Embryo
CA   Transformed cell line
DT   Created: 10-04-15; Last updated: 19-12-24; Version: 12
//
RX   PubMed=8134344; DOI=10.1073/pnas.91.6.2026; PMCID=PMC43302;
RA   Lowe S.W., Jacks T., Housman D.E., Ruley H.E.;
RT   "Abrogation of oncogene-associated apoptosis allows transformation of
RT   p53-deficient cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 91:2026-2030(1994).
//